Table 2 Differences in values of hematological parameters and STMs between the wild-type and mutant KRAS groups
KRAS Wild-type | KRAS Mutantion | P | |||||
|---|---|---|---|---|---|---|---|
N | Median | Std.dev | N | Median | Std.dev | ||
Age | 508 | 58.00 | 12.54 | 276 | 58.00 | 11.29 | 0.154 |
Tumor location | 508 | 276 | 0.019 | ||||
Ascending colon | 115 (14.7)a | – | – | 91 (11.6) | – | – | |
Transverse colon | 27 (3.4) | – | – | 12 (1.5) | – | – | |
Descending colon | 32 (4.1) | – | – | 17 (2.2) | – | – | |
Sigmoid | 106 (13.5) | – | – | 40 (5.1) | – | – | |
Rectum | 228 (29.1) | – | – | 116 (14.8) | – | – | |
CEA | 508 | 3.70 | 124.99 | 276 | 4.80 | 196.67 | < 0.001 |
CA125 | 508 | 12.25 | 103.17 | 276 | 11.20 | 35.23 | 0.175 |
CA199 | 508 | 8.00 | 220.29 | 276 | 12.40 | 706.28 | < 0.001 |
AFP | 455 | 2.60 | 66.93 | 265 | 2.60 | 6.52 | 0.277 |
SCC | 358 | 0.70 | 1.72 | 189 | 0.70 | 0.49 | 0.348 |
NSE | 435 | 16.01 | 8.26 | 263 | 15.27 | 22.93 | 0.043 |
CA72.4 | 435 | 2.38 | 41.83 | 263 | 2.34 | 45.43 | 0.863 |
CA15.3 | 378 | 7.30 | 4.99 | 194 | 7.25 | 4.11 | 0.941 |
FERR | 341 | 63.80 | 301.84 | 186 | 48.25 | 269.67 | 0.066 |
CYFRA21.1 | 358 | 2.12 | 10.42 | 189 | 2.25 | 11.52 | 0.279 |
WBC | 508 | 5.93 | 2.19 | 276 | 5.59 | 2.13 | 0.003 |
MON | 508 | 0.43 | 0.19 | 276 | 0.38 | 0.16 | 0.846 |
MLR | 508 | 0.29 | 0.19 | 276 | 0.25 | 0.12 | < 0.001 |
Mon% | 508 | 7.29 | 2.60 | 276 | 6.78 | 2.36 | 0.005 |
HCT | 508 | 37.05 | 6.28 | 276 | 36.55 | 6.64 | 0.031 |
HGB | 508 | 123.00 | 23.54 | 276 | 119.00 | 25.73 | 0.030 |
AVEMPV | 423 | 13.90 | 2.67 | 222 | 13.50 | 2.61 | 0.016 |
MCH | 508 | 29.30 | 3.77 | 276 | 29.00 | 4.18 | 0.015 |
MCHC | 508 | 328.00 | 14.98 | 276 | 329.00 | 18.25 | 0.292 |
MCV | 508 | 88.60 | 8.97 | 276 | 87.20 | 9.68 | 0.019 |
HDLC | 443 | 1.08 | 0.33 | 246 | 1.16 | 0.31 | 0.006 |