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Table 2 Differences in values of hematological parameters and STMs between the wild-type and mutant KRAS groups

From: The value of haematological parameters and serum tumour markers for predicting KRAS mutations in 784 Chinese colorectal cancer patients: a retrospective analysis

  KRAS Wild-type KRAS Mutantion P
N Median Std.dev N Median Std.dev
Age 508 58.00 12.54 276 58.00 11.29 0.154
Tumor location 508    276    0.019
Ascending colon 115 (14.7)a 91 (11.6)  
Transverse colon 27 (3.4) 12 (1.5)  
Descending colon 32 (4.1) 17 (2.2)  
Sigmoid 106 (13.5) 40 (5.1)  
Rectum 228 (29.1) 116 (14.8)  
CEA 508 3.70 124.99 276 4.80 196.67 < 0.001
CA125 508 12.25 103.17 276 11.20 35.23 0.175
CA199 508 8.00 220.29 276 12.40 706.28 < 0.001
AFP 455 2.60 66.93 265 2.60 6.52 0.277
SCC 358 0.70 1.72 189 0.70 0.49 0.348
NSE 435 16.01 8.26 263 15.27 22.93 0.043
CA72.4 435 2.38 41.83 263 2.34 45.43 0.863
CA15.3 378 7.30 4.99 194 7.25 4.11 0.941
FERR 341 63.80 301.84 186 48.25 269.67 0.066
CYFRA21.1 358 2.12 10.42 189 2.25 11.52 0.279
WBC 508 5.93 2.19 276 5.59 2.13 0.003
MON 508 0.43 0.19 276 0.38 0.16 0.846
MLR 508 0.29 0.19 276 0.25 0.12 < 0.001
Mon% 508 7.29 2.60 276 6.78 2.36 0.005
HCT 508 37.05 6.28 276 36.55 6.64 0.031
HGB 508 123.00 23.54 276 119.00 25.73 0.030
AVEMPV 423 13.90 2.67 222 13.50 2.61 0.016
MCH 508 29.30 3.77 276 29.00 4.18 0.015
MCHC 508 328.00 14.98 276 329.00 18.25 0.292
MCV 508 88.60 8.97 276 87.20 9.68 0.019
HDLC 443 1.08 0.33 246 1.16 0.31 0.006
  1. CEA Carcinoembryonic antigen, CA 125 Carbohydrate antigen 125, CA 19–9 Carbohydrate antigen 19–9, SCC Squamous cell carcinoma antigen, NSE Neuronspecific enolase, CA 724 Carbohydrate antigen 72–4, FERR Ferritin, CYFRA21-1 Human cytokeratin fragment antigen 21–1, WBC White blood cell, MON Monocyte, MLR Monocyte /Lymphocyte, HCT Hematocrit, HGB Hemoglobin, AVEMPV Mean platelet volume, MCH Mean corpuscular hemoglobin, MCHC Mean corpusular hemoglobin concerntration, MCV Mean corpuscular volume, HDLC High-density lipoprotein
  2. aThe percentage in brackets represents the percentage of the total number of patients
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