Table 2 Characteristics of studies entered into the meta-analysis
From: Diagnostic value of serum HER2 levels in breast cancer: a systematic review and meta-analysis
Author | Year | Country | No. of cases | Reference method | Detection method | Cut-off value |
|---|---|---|---|---|---|---|
Kong [17] | 2006 | Korea | 195 | IHC/FISH | CLIA | 15 μg/L |
Olsen [22] | 2007 | Germany | 118 | IHC/FISH | ELISA/ CLIA | 15 ng/mL |
Ludovini [23] | 2008 | Italy | 256 | IHC/FISH | ELISA/ CLIA | 15 ng/mL |
Papadopoulou [24] | 2008 | Greece | 56 | a | ELISA | 1.98 ng/ml |
Savino [25] | 2009 | Italy | 85 | IHC | ELISA | 22 ng/mL |
Finn [26] | 2009 | – | 579 | IHC/FISH | ELISA | 16 ng/mL |
Farzadnia [27] | 2010 | Iran | 75 | IHC | ELISA | 18.4 ng/ml |
Lauterlein [28] | 2011 | Denmark | 311 | IHC/FISH | CLIA | 12.2 mg/L |
Sørensen [29] | 2013 | Denmark | 540 | IHC/FISH | CLIA | 15 μg/L |
Pedersen [30] | 2013 | Denmark | 107 | IHC/FISH | CLIA | 15 μg/L |
Di Gioia [31] | 2014 | Germany | 565 | IHC/FISH | CLIA | 15 ng/mL |
Di Gioia [32] | 2015 | Germany | 241 | IHC/FISH | CLIA | 15 ng/mL |
Banys-Paluchowski [33] | 2017 | Germany | 251 | IHC/FISH | ELISA | 15 ng/mL |
Broughton [34] | 2017 | Norway | 149 | IHC/FISH | CLIA | 15.2 μg/L |