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Table 4 Regulation of biological function “positive regulation of apoptotic signaling pathway” by cetuximab, afatinib and trastuzumab + afatinib

From: Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines

Condition ID Description GeneRatio BgRatio p.adjust
MKN1 24 h Cet vs. MKN1 24 h untr GO:2001235 positive regulation of apoptotic signaling pathway 2/162 156/14021 6.82E-01
MKN1 24 h Afa vs. MKN1 24 h untr GO:2001235 positive regulation of apoptotic signaling pathway 5/463 156/14021 7.57E-01
MKN1 24 h Tra + Afa vs. MKN1 24 h untr GO:2001235 positive regulation of apoptotic signaling pathway 5/483 156/14021 8.11E-01
MKN7 24 h Afa vs. MKN7 24 h untr GO:2001235 positive regulation of apoptotic signaling pathway 15/1744 156/14021 9.87E-01
MKN7 24 h Tra + Afa vs. MKN7 24 h untr GO:2001235 positive regulation of apoptotic signaling pathway 17/1781 156/14021 9.59E-01
NCI-N87 24 h Afa vs. NCI-N87 24 h untr GO:2001235 positive regulation of apoptotic signaling pathway 62/4359 156/14021 1.41E-01
NCI-N87 24 h Tra + Afa vs. NCI-N87 24 h untr GO:2001235 positive regulation of apoptotic signaling pathway 72/4772 156/14021 1.75E-02
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BMC Cancer

ISSN: 1471-2407

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