Table 4 Regulation of biological function “positive regulation of apoptotic signaling pathway” by cetuximab, afatinib and trastuzumab + afatinib
Condition | ID | Description | GeneRatio | BgRatio | p.adjust |
|---|---|---|---|---|---|
MKN1 24 h Cet vs. MKN1 24 h untr | GO:2001235 | positive regulation of apoptotic signaling pathway | 2/162 | 156/14021 | 6.82E-01 |
MKN1 24 h Afa vs. MKN1 24 h untr | GO:2001235 | positive regulation of apoptotic signaling pathway | 5/463 | 156/14021 | 7.57E-01 |
MKN1 24 h Tra + Afa vs. MKN1 24 h untr | GO:2001235 | positive regulation of apoptotic signaling pathway | 5/483 | 156/14021 | 8.11E-01 |
MKN7 24 h Afa vs. MKN7 24 h untr | GO:2001235 | positive regulation of apoptotic signaling pathway | 15/1744 | 156/14021 | 9.87E-01 |
MKN7 24 h Tra + Afa vs. MKN7 24 h untr | GO:2001235 | positive regulation of apoptotic signaling pathway | 17/1781 | 156/14021 | 9.59E-01 |
NCI-N87 24 h Afa vs. NCI-N87 24 h untr | GO:2001235 | positive regulation of apoptotic signaling pathway | 62/4359 | 156/14021 | 1.41E-01 |
NCI-N87 24 h Tra + Afa vs. NCI-N87 24 h untr | GO:2001235 | positive regulation of apoptotic signaling pathway | 72/4772 | 156/14021 | 1.75E-02 |