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Fig. 6 | BMC Cancer

Fig. 6

From: Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines

Fig. 6

Effects of trastuzumab and afatinib on cell motility and average speed. MKN1 (a, b), MKN7 (c, d) NCI-N87 (e, f) and Hs746T (g, h) cells were treated with 5 μg/ml trastuzumab (Tra), 0.5 μM afatinib (Afa), 5 μg/ml trastuzumab + 0.5 μM afatinib (Tra + Afa) or afatinib solvent DMSO (0.05%). Untreated (untr) cells were used as control. Time-lapse microscopy was carried out for 7 h. Cell movement was tracked to assess motility (a, c, e, g) and average speed (b, d, f, h). Shown are the mean values of three to six experiments with standard deviation. Statistically significant effects are indicated by *p < 0.05 or **p < 0.01 (two-sample t-test)

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