From: The majority of β-catenin mutations in colorectal cancer is homozygous
Cohort | Diagnostic | Diagn. MSS | Diagn. MSI-H | Scientific |
---|---|---|---|---|
CTNNB1 mutated | 16/839 (1.9%) | 9 | 7 | 11/30 (37%) |
biallelic | 12/16 | 7/9 | 5/7 | 8/11 |
homozygous | 6 | 2 | 4 | 7 |
homo- or hemizygous | 6 | 5 | 1 | 1 |
heterozygous | 4 | 2 | 2 | 3 |