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Table 1 Summarized results of CTNNB1 mutations both, diagnostic and scientific cohorts. CTNNB1 mutated CRCs of diagnostic cohort were further split according to MSI status. For detailed description of individual cases, see Supplementary Table 1

From: The majority of β-catenin mutations in colorectal cancer is homozygous

Cohort Diagnostic Diagn. MSS Diagn. MSI-H Scientific
CTNNB1 mutated 16/839 (1.9%) 9 7 11/30 (37%)
 biallelic 12/16 7/9 5/7 8/11
 homozygous 6 2 4 7
 homo- or hemizygous 6 5 1 1
heterozygous 4 2 2 3
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