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Fig. 2 | BMC Cancer

Fig. 2

From: The majority of β-catenin mutations in colorectal cancer is homozygous

Fig. 2

Differences between CTNNB1 mutations in MSI-H and MSS cancers. In MSI-H tumours CTNNB1 mutations cluster exclusively at codons 41 and 45 and mainly consist of missense mutations. In MSS cancers CTNNB1 mutations frequently cover the ß-TrcP binding site and consist of larger in frame deletions. Captation: squares white: deletion, MSI-H; squares black: deletion, MSS; circles white: missense mutation, MSI-H; circles black: missense mutation, MSS

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