Fig. 4
From: Cell type-specific genotoxicity in estrogen-exposed ovarian and fallopian epithelium
Differential requirement of BRCA1/BRCA2 by OvCa cells upon estrogen exposure. a-b, Quantifications for 53BP1 or γH2AX foci in A549 (a) and L02 (b) cells after estrogen treatment (50 nM) for 6 h. No elevation of DSBs was observed in these cells. c-f, Quantifications for 53BP1 foci formation in HO-8910 (a), HO-8910 PM (b), OVCAR-8TR (c) and SKOV3 (d) cells treated for estrogen for 6 h. p values: unpaired t-test. NS: not statistically significant