Clinicopathological characteristics, treatment and prognosis of head & neck small cell carcinoma: a SEER population-based study

Table 1 The summary of H&NSmCC patients’ clinico-pathologic characteristics

Clinicopathologic parameter	Disease specific survival				Overall survival
Clinicopathologic parameter	Alive	Dead	Total	P-value	Alive	Dead	Total	P-value
Age
0–19	2	4	507	0.085	2	4	789	0.001
20–29	4	9			4	9
30–39	12	9			12	14
40–49	20	36			21	47
50–59	35	89			38	119
60–69	39	98			50	170
70–79	22	71			27	158
80+	12	45			15	99
Race
Black	12	31	506	0.773	12	51	788	0.624
White	123	311			145	539
Others	10	19			11	30
Gender
Female	33	134	507	0.002	41	236	789	0.001
Male	113	227	507	0.002	128	384	789	0.001
Marital status at diagnosis
Single	31	57	482	0.011	32	75	747	0.001
Married	85	192			99	336
Other status	21	96			27	178
Insurance status
Any Medicaid	13	18	224	0.172	14	30	333	0.040
Insured	81	101			99	177
Uninsured	8	3			9	4
Tumor site
Oral cavity	10	29	501	0.000	12	49	781	0.000
Salivary gland	46	63			54	144
Pharynx & Larynx	29	92			33	142
Nasal cavity & accessory sinuses	34	48			39	80
Glottis	21	91			24	140
Thyroid gland	3	35			3	61
Pathological grade
Grade I	2	1	321	0.052	2	1	502	0.001
Grade II	3	3			4	3
Grade III	31	75			37	128
Grade IV	43	163			47	280
AJCC stage
I stage	13	11	234	0.000	15	21	334	0.000
II stage	16	9			18	14
III stage	22	20			25	35
IV stage	40	103			42	164
T stage
T1	34	51	254	0.594	42	88	374	0.207
T2	27	40			29	65
T3	12	30			13	57
T4	22	38			23	57
N stage
N0	49	45	254	0.003	54	82	374	0.005
N1	19	33			24	56
N2	23	66			24	101
N3	1	6			1	10
NX	3	9			4	18
M stage
M0	90	102	254	0.000	100	183	374	0.000
M1	3	49			3	71
MX	2	8			4	13
Surgery
Yes	79	138	217	–	94	261	356	0.549
No	0	0	217	–	0	1	356	0.549
Radiotherapy
Yes	31	135	507	0.000	34	248	789	0.000
No	115	226	507	0.000	135	372	789	0.000
Chemotherapy
Yes	35	140	507	0.001	43	270	789	0.000
No	111	221	507	0.001	126	350	789	0.000

ISSN: 1471-2407