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Fig. 2 | BMC Cancer

Fig. 2

From: Role of circulating free DNA in evaluating clinical tumor burden and predicting survival in Chinese metastatic colorectal cancer patients

Fig. 2

Correlation between cfDNA and tumor burden. a The concentration and content of cfDNA were significantly correlated with the levels of CEA and LDH and the sum of tumor diameters. b Through ROC curve analysis, the optimal cutoff level for cfDNA concentration was determined to be 17.91 ng/ml. c The median progression-free survival (11.7 versus 6.6 months, P < 0.0001) was significantly different between patients with a low cfDNA concentration (≤17.91 ng/ml) and those with a high cfDNA concentration (> 17.91 ng/ml). d Patients with a low cfDNA concentration had a higher 1-year overall survival rates (94% versus 56%, P < 0.0001) than those with a high cfDNA concentration. e An early decrease in cfDNA was related to a good therapeutic effect in two typical mCRC patients

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BMC Cancer

ISSN: 1471-2407

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