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Table 1 Characteristics of patients, primary tumours, oligometastatic tumours and SBRT characteristics

From: Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival

Characteristic

Distribution

Number (%)

All tumours

 

1547

Sex

Male

994 (64.3)

 

Female

553 (35.7)

Age, years

Median, range, IQR

72; 16–93; 63–78

ECOG Performance Status

0

841 (54.4)

 

1

529 (34.2)

 

2

90 (5.8)

 

3

19 (1.2)

 

Missing

68 (4.4)

Primary lesion sites

Lung

451 (29.2)

 

Colorectum

391 (25.3)

 

Head and Neck

126 (8.1)

 

Oesophagus

132 (8.5)

 

Others

447 (28.9)

Pathology of primary lesion

Adenocarcinoma

861 (55.7)

 

Squamous cell carcinoma

396 (25.6)

 

Sarcoma

47 (3.0)

 

Others

168 (10.9)

 

Missing

75 (4.8)

Control method of primary lesion

Surgery

1222 (79.0)

 

Chemoradiation

130 (8.4)

 

Radiation (X-ray or particle)

70 (4.5)

 

Others

40 (2.6)

 

Missing

85 (5.5)

Disease-free interval, months

Median, range, IQR

17.5; 0–423.9; 8.0–34.3

Oligometastatic state

Oligo-recurrences

1157 (74.8)

 

Sync-oligometastases

133 (8.6)

 

Unclassified

133 (8.6)

 

Missing

124 (8.0)

SBRT performed institution

Academic

642 (41.5)

 

Non-academic

905 (58.5)

Date SBRT was performed

2004–2009

518 (33.5)

 

2010–2015

1029 (66.5)

Chemotherapy

Before SBRT

Yes, 591 (38.2)

No, 945 (61.1)

Missing, 11 (0.7)

 

Concurrent with SBRT

Yes, 34 (2.2)

No, 1513 (97.8)

 

After SBRT

Yes, 242 (15.6)

No, 998 (64.5)

Missing, 307 (19.9)

Maximum tumour diameter, cm

Median, range, IQR

1.5; 0.3–6.5; 1.0–2.0

Number of oligometastases at the time of emergence of the SBRT-targeted tumour

1

1036 (67.0)

2–5

503 (32.5)

Missing

8 (0.5)

Lung lobe involved with treated tumour

Right upper lobe

293 (18.9)

Right middle lobe

83 (5.4)

 

Right lower lobe

321 (20.8)

 

Left upper lobe

294 (19.0)

 

Left lower lobe

226 (14.6)

 

Unknown lobe

Right lung, 12; Left lung, 7

 

Missing

311 (20.1)

Beams

Multiple static

1145 (74.0)

 

Arc

401 (25.9)

 

Missing

1 (0.1)

X-ray energy

4 MV only

202 (13.1)

 

6 MV only

1179 (76.2)

 

Others

160 (10.3)

 

Missing

6 (0.4)

Field coplanarity

Coplanar field

1139 (73.6)

 

Non-coplanar field

404 (26.1)

 

Missing

4 (0.3)

Dose calculation algorithm

Type A

541 (35.0)

 

Type B

799 (51.6)

 

Type C

144 (9.3)

 

Missing

63 (4.1)

Dose prescription

IC

1103 (71.3)

 

D95 of PTV

317 (20.5)

 

Others

127 (8.2)

BED10 at isocenter, Gy

Median, range, IQR

105.6; 75.0–289.5; 105.6–126.9

Number of SBRT fractions

2–3

27 (1.7)

 

4

959 (62.0)

 

5

236 (15.3)

 

6–16

324 (20.9)

 

missing

1 (0.1)

OTT of SBRT, day

Median, range, IQR

7; 3–81; 4–11

  1. Abbreviations: SBRT Stereotactic body radiotherapy, IQR Interquartile range, ECOG Eastern Cooperative Oncology Group, IC Isocenter, D95 of PTV Dose covering 95% of planning target volume, BED Biological effective dose, OTT Overall treatment time