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Table 1 Demographics, clinical and surgical data, oncological treatment, and outcomes for women 18–40 years old diagnosed with epithelial ovarian cancer in Sweden 2008–2015

From: A Swedish Nationwide prospective study of oncological and reproductive outcome following fertility-sparing surgery for treatment of early stage epithelial ovarian cancer in young women

 

Treated with FSS

Treated with RS

P-value

N (%)

36 (43)

47 (57)

 

Mean age, years (range)

29 (19–39)

37 (26–40)

< 0.001

Previous parity, n (%)

  

< 0.001

 0

27 (75)

16 (34)

 

 1

6 (17)

7 (15)

 

 2

2 (6)

17 (36)

 

 ≥3

0

4 (9)

 

FIGO stage, n (%)

  

0.002

 IA

27 (75)

18 (38)

 

 IB

 

 IC

9 (25)

29 (62)

 

IC1

6

19

 

IC2

3

6

 

IC3

0

2

 

IC unspecified

0

2

 

Histologic type, n (%)

 Serous, high-grade

2 (6)

6 (13)

 

 Serous, low-grade

1 (3)

2 (4)

 

 Mucinous

18 (50)

12 (26)

 

 Endometrioid

10 (28)

12 (26)

 

Grade 1

6

4

 

Grade 2

2

3

 

Grade 3

1

3

 

 Clear cell

3 (8)

13 (28)

 

Other a

2 (6)

2 (4)

 

Surgical mode,b n (%)

27 (75)

41 (87)

0.241

Open

6 (17)

3 (6)

 

Laparoscopy

Robot

3 (8)

3 (6)

 

Type of surgery, n (%)

 Primary

17 (47)

20 (43)

0.824

 Re-staging

19 (53)

27 (57)

 

Type of staging procedure, n (%)

 Cytology

33 (92)

39 (83)

 

 Peritoneal biopsies

30 (83)

39 (83)

 

 Oment biopsy

31 (86)

45 (96)

 

 LN pelvic

8 (22)

24 (51)

 

 LN paraaortic

8 (22)

22 (47)

 

Adjuvant chemotherapy, n (%)

14 (39)

34 (72)

0.003

Histologic review,c

n (%)

33 (92)

42 (89)

1.0

Recurrence, n (%)

2 (6)

6 (13)

 

Died of disease, n (%)

1 (3)

2 (4)

 

Follow-up, months,

mean (range)

63 (16–111)

64 (21–112)

0.708

  1. a Mixed type, adenocarcinoma unspecified; b If primary surgery is laparoscopic and re-staging laparotomy, patient is classified as laparotomy; c Histologic review by a pathologist with expertise in gynecologic oncology; FSS Fertility-sparing surgery, RS Radical surgery, LN Lymph node