Skip to main content

Table 2 Overall survival according to ICC-positive cell type status in bone marrow

From: Cytokeratin-positive cells in the bone marrow from patients with pancreatic, periampullary malignancy and benign pancreatic disease show no prognostic information

ICC-type Level N Incidentcases Person months HR(95%CI) p-value Mean OS(95%CI)
Overall survival, resected cancers
TC Positive 6 5 217.5 1.1 (0.4–2.3) 0.865 36.2 (11.3–61.2)
Negative 162 133 5293.6    37.1 (31.6–42.6)
UIC Positive 10 7 488.1 0.6 (0.3–1.3) 0.197 52.5 (27.2–77.7)
Negative 164 136 5144.0    35. 6 (30.2–40.9)
HC Positive 16 14 431.6 1.3 (0.7–2.2) 0.386 29.6 (14.3–44.8)
Negative 153 125 5006.5    37.3 (31.6–43.1)
QHC Positive 12 10 419.0 0.9 (.5–1.8) 0.795 37.1 (18.1–56.0)
Negative 123 102 3817.1    35.5 (29.2–41.8)
Overall survival, advanced cancers
TC Positive 2 2 7.9 3.4 (0.7–15.4) 0.114 3.9 (0.8–7.1)s
Negative 29 29 298.8    10.3 (7.4–13.2)
UIC Positive 0 0   
Negative 31 31 306.6    9.9 (7.1–12.7)
HC Positive 2 2 14.3 1.6 (0.4–7.2) 0.522 7.2 (4.0–10.3)
Negative 28 28 266.6    9.5 (6.5–12.5)
QHC Positive 3 3 16.6 2.1 (0.6–7.2) 0.262 5.5 (1.9–9.2)
Negative 25 25 248.5    9.9 (6.5–13.4)
Overall survival, benign disease
TC Positive 4 2 256.1 4.0 (0.7–22.6) 0.114 65.3 (53.0–77.6)
Negative 25 7 1929.4    92.2 (82.7–101.7)
UIC Positive 2 2 143.0 5.7 (1.1–25.5) 0.039 71.5 (52.9–90.1)
Negative 28 7 1796.9    92.6 (83.2–101.9)
HC Positive 3 2 202.3 4.7 (0.9–25.7) 0.075 69.4 (43.1–95.7)
Negative 26 6 1867.3    93.7 (84.3–103.2)
QHC Positive 3 2 202.3 3.9 (0.7–21.6) 0.114 5.5 (1.9–9.2)
Negative 22 5 1639.1    9.9 (6.5–13.4)
Disease free survival, resected cancers
TC Positive 6 6 112.4 1.3 (0.6–3.0) 0.525 18.7 (4.5–33.0)
Negative 162 126 4022.2    32.2 (25.9–38.5)
UIC Positive 10 5 441.8 0.4 (0.2–1.0) 0.040 62.1 (37.1–87.1)
Negative 164 132 3785.8    29.4 (23.5–35.4)
HC Positive 16 16 299.4 1.4 (0.8–2.5) 0.277 22.6 (5.7–39.5)
Negative 153 120 3774.0    31.9 (25.5–38.3)
QHC Positive 12 10 340.7 1.0 (0.5–1.9) 0.973 30.1 (10. 1–50.8)
Negative 123 96 2825.6    30.8 (23.7–37.8)
  1. Detailed survival analysis for patients with (pos.) or without (neg.) ICC-positive cells in the bone marrow in the indicated morphological cell categories. HR and p-values were computed by Cox-regression analysis. The number of patients analysed may differ from group size for cases with inconclusive ICC-results
\