| |
Overall
|
< 65 years
|
65–74 years
|
75–84 years
|
85+ years
|
|---|
|
Non-transplant (N = 22,062)
|
Transplant (N = 2763)
|
Non-transplant (n = 5197)
|
Transplant (n = 1378)
|
Non-transplant (n = 7741)
|
Transplant (n = 1298)
|
Non-transplant (n = 7536)
|
Transplant (n = 87)
|
Non-transplant (n = 1588)
|
Transplant (n = 0)
|
|---|
|
Charlson Comorbidity Index during 180 days prior to index MM diagnosis
|
|
Mean (SD)
|
1.5 (1.8)
|
1.2 (1.5)
|
0.9 (1.6)
|
0.7 (1.3)
|
1.5 (1.8)
|
1.6 (1.6)
|
1.6 (1.8)
|
1.5 (1.3)
|
2.1 (1.9)
|
–
|
|
Median (Q1–Q3)
|
1.0 (0–2.0)
|
1.0 (0–2.0)
|
0 (0–1.0)
|
0 (0–1.0)
|
1.0 (0–2.0)
|
2.0 (0–2.0)
|
1.0 (0–2.0)
|
2.0 (0–2.0)
|
2.0 (0–3.0)
|
–
|
|
Min, max
|
0, 13
|
0, 11
|
0, 13
|
0, 9
|
0, 12
|
0, 11
|
0, 12
|
0, 5
|
0, 10
|
–
|
|
Comorbidities during 180 days prior to index MM diagnosis, n (%)
|
|
Any comorbidity below
|
14,539 (65.9)
|
1638 (59.3)
|
2556 (49.2)
|
746 (54.1)
|
5186 (67.0)
|
826 (63.6)
|
5476 (72.7)
|
66 (75.9)
|
1321 (83.2)
|
–
|
|
Cardiac arrhythmia
|
4327 (19.6)
|
294 (10.6)
|
529 (10.2)
|
139 (10.1)
|
1396 (18.0)
|
143 (11.0)
|
1854 (24.6)
|
12 (13.8)
|
548 (34.5)
|
–
|
|
Congestive heart failure
|
2984 (13.5)
|
117 (4.2)
|
493 (9.5)
|
NR
|
956 (12.3)
|
59 (4.5)
|
1179 (15.6)
|
NR
|
356 (22.4)
|
–
|
|
Hypertension, complicated
|
3718 (16.9)
|
260 (9.4)
|
603 (11.6)
|
NR
|
1274 (16.5)
|
143 (11.0)
|
1435 (19.0)
|
NR
|
406 (25.6)
|
–
|
|
Hypertension, simple
|
11,698 (53.0)
|
1316 (47.6)
|
1871 (36.0)
|
569 (41.3)
|
4215 (54.5)
|
692 (53.3)
|
4490 (59.6)
|
55 (63.2)
|
1122 (70.7)
|
–
|
|
Hepatic disease
|
972 (4.4)
|
151 (5.5)
|
269 (5.2)
|
NR
|
392 (5.1)
|
71 (5.5)
|
241 (3.2)
|
NR
|
70 (4.4)
|
–
|
|
Pulmonary circulation disorders
|
1027 (4.7)
|
56 (2.0)
|
172 (3.3)
|
NR
|
357 (4.6)
|
23 (1.8)
|
388 (5.1)
|
NR
|
110 (6.9)
|
–
|
|
Renal impairment
|
5317 (24.1)
|
471 (17.0)
|
932 (17.9)
|
230 (16.7)
|
1829 (23.6)
|
222 (17.1)
|
2028 (26.9)
|
19 (21.8)
|
528 (33.2)
|
–
|
|
Valvular disease
|
2258 (10.2)
|
158 (5.7)
|
282 (5.4)
|
NR
|
744 (9.6)
|
90 (6.9)
|
966 (12.8)
|
NR
|
266 (16.8)
|
–
|
- MM Multiple myeloma, NDMM Newly diagnosed multiple myeloma, NR Not reported, Q Quartile, SD Standard deviation
- Values of 1–10 have not been reported in any cell in this table to conform to the Centers for Medicare and Medicaid Services cell size suppression policy; Similarly, values have not been reported for categorical variables and by subgroup to avoid making it possible to calculate the values of the NR cells
