|
Location
|
|
Lower Limb
|
1536
|
82.8%
|
506
|
86.2%
|
2042
|
83.6%
|
0.053
|
|
Upper Limb
|
319
|
17.2%
|
81
|
13.8%
|
400
|
16.4%
|
|
Long vs Short Bone
|
|
Short Bone
|
51
|
2.8%
|
49
|
8.5%
|
100
|
4.1%
|
p < 0.001
|
|
Long Bone
|
1789
|
97.2%
|
527
|
91.5%
|
2316
|
95.9%
|
|
AJCC Clinical Stage
|
|
Stage 2A or 2B
|
1509
|
81.3%
|
438
|
74.6%
|
1947
|
79.7%
|
p = 0.002
|
|
Stage 3
|
63
|
3.4%
|
25
|
4.3%
|
88
|
3.6%
|
|
Stage 4A or 4B
|
283
|
15.3%
|
124
|
21.1%
|
407
|
16.7%
|
|
Osteosarcoma Type
|
|
Osteosarcoma NOS
|
1216
|
66.1%
|
407
|
70.7%
|
1623
|
67.2%
|
0.059
|
|
Chondro/Fibroblastic
|
370
|
20.1%
|
111
|
19.3%
|
481
|
19.9%
|
|
Telangiectatic
|
78
|
4.2%
|
24
|
4.2%
|
102
|
4.2%
|
|
Central
|
108
|
5.9%
|
24
|
4.2%
|
132
|
5.5%
|
|
Surface/Juxtacortical
|
68
|
3.7%
|
10
|
1.7%
|
78
|
3.2%
|
|
Tumor Size (cm); mean (95% CI)
|
11.6
|
11.0–12.1
|
13.1
|
12.2–13.9
|
11.9
|
11.5–12.4
|
0.005
|
|
< 8 cm
|
547
|
30.6%
|
132
|
23.0%
|
679
|
28.7%
|
p < 0.001
|
|
> 8 cm
|
1242
|
69.4%
|
442
|
77.0%
|
1684
|
71.3%
|
|
Presence of Metastases at Dx
|
|
No metastases
|
1549
|
84.7%
|
454
|
78.3%
|
2003
|
83.2%
|
p < 0.001
|
|
metastases
|
279
|
15.3%
|
126
|
21.7%
|
405
|
16.8%
|
|
Comorbidities at Dx
|
|
No comorbidities
|
1714
|
92.4%
|
520
|
88.6%
|
2234
|
91.5%
|
0.004
|
|
1 or more
|
141
|
7.6%
|
67
|
11.4%
|
208
|
8.5%
|
|
Received Adjuvant Chemotherapy
|
|
No
|
81
|
4.4%
|
62
|
10.6%
|
143
|
5.9%
|
p < 0.001
|
|
Yes
|
1762
|
95.6%
|
521
|
89.4%
|
2283
|
94.1%
|
|
Sequence of Adjuvant Treatment
|
|
Before
|
558
|
37.3%
|
170
|
38.7%
|
728
|
37.6%
|
p < 0.001
|
|
After
|
162
|
10.8%
|
88
|
20.0%
|
250
|
12.9%
|
|
Before+After
|
777
|
51.9%
|
181
|
41.2%
|
958
|
49.5%
|
|
Surgical Margins
|
|
Clear
|
1617
|
93.7%
|
541
|
96.6%
|
2158
|
94.4%
|
p = 0.010
|
|
Positive
|
108
|
6.3%
|
19
|
3.4%
|
127
|
5.6%
|
|
Unplanned Readmission After Surgery
|
|
No Unplanned Readmiss
|
1727
|
96.2%
|
548
|
95.6%
|
2275
|
96.1%
|
0.537
|
|
Unplanned Readmission
|
68
|
3.8%
|
25
|
4.4%
|
93
|
3.9%
|
|
Inpatient Days after Surgery; mean (95% CI)
|
6.7
|
6.3–7.1
|
6.3
|
5.6–7.1
|
6.6
|
6.3–7.1
|
0.3706
|
|
Days from Dx to Surgery; mean (95% CI)
|
96.1
|
94.1–98.1
|
91.8
|
87.6–96.1
|
95.1
|
93.3–96.9
|
0.049
|
|
Days from Dx to Treatment Commencing; mean (95% CI)
|
20.5
|
19.4–21.5
|
22.4
|
20.3–24.5
|
20.9
|
20.0–21.9
|
0.0796
|
|
Total
|
1855
|
75.96%
|
587
|
24.04%
|
2442
|
100%
| |
