Limb salvage versus amputation in patients with osteosarcoma of the extremities: an update in the modern era using the National Cancer Database

Table 1 Demographic characteristics of patients undergoing limb salvage surgery vs. amputation

	Type of Surgery						p value
	Limb Salvage Surgery		Amputation		Total
	n	%	n	%	n	%
Age; median (IQR)	17	(13–28)	21	(14–45)	18	(13–32)	< 0.0001
< 20	1135	61.2%	267	45.5%	1402	57.4%	< 0.0001
20–39	399	21.5%	152	25.9%	551	22.6%
40–59	199	10.7%	98	16.7%	297	12.2%
60+	122	6.6%	70	11.9%	192	7.9%
Sex
Male	1095	59.0%	377	64.2%	1472	60.3%	0.025
Female	760	41.0%	210	35.8%	970	39.7%	0.025
Race
White	1398	75.4%	436	74.3%	1834	75.1%	0.923
Black	295	15.9%	98	16.7%	393	16.1%
Asian/Pacific Islander	80	4.3%	28	4.8%	108	4.4%
Other/Unknown	82	4.4%	25	4.3%	107	4.4%
Insurance Status
Uninsured	69	3.9%	33	5.7%	102	4.3%	< 0.0001
Insured	1207	67.5%	316	54.9%	1523	64.4%
Medicaid	418	23.4%	168	29.2%	586	24.8%
Medicare	94	5.3%	59	10.2%	153	6.5%
Zipcode Income
< $38,000	345	18.8%	105	18.2%	450	18.7%	0.002
$38,000–$47,999	398	21.7%	158	27.4%	556	23.1%
$48,000–$62,999	476	26.0%	163	28.3%	639	26.5%
$63,000+	615	33.5%	150	26.0%	765	31.7%
Zipcode Education
21% or more	381	20.8%	112	19.4%	2009	85.1%	0.258
13–20.9%	443	24.1%	163	28.3%	316	13.4%
7–12.9%	568	31.0%	169	29.3%	36	1.5%
< 7%	443	24.1%	132	22.9%	575	23.8%
Urban
Metro	1539	85.8%	470	82.7%	2817	85.2%	0.052
Urban	232	12.9%	84	14.8%	436	13.2%
Rural	22	1.2%	14	2.5%	54	1.6%
Distance from Hospital (Miles); mean (95% CI)	70.4	(63.30–77.53)	59.4	(51.20–67.65)	67.8	(62.03–73.55)	0.1103
Year of Diagnosis
< 2006	279	15.0%	97	16.5%	376	15.4%	0.067
2006–2010	748	40.3%	260	44.3%	1008	41.3%
2011–2015	828	44.6%	230	39.2%	1058	43.3%
Total	1855	75.96%	587	24.04%	2442	100%

ISSN: 1471-2407