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Table 3 Clearance and persistency rates of HR-HPV infections at the different follow-up intervals with the corresponding Odds ratio and p-values

From: 14-type HPV mRNA test in triage of HPV DNA-positive postmenopausal women with normal cytology

Follow-up interval (Number of evaluated patients and their types of HR-HPV infection)

Clearance rate (%)a

Persistency rate (%)b

Odds ratio (95% CI)

P-value

I follow-up (Total Number n = 271)

 HPV mRNA pos/ DNA pos = 110

n = 112 (41.3%)

n = 159 (58.6%)

29.2 (13.2–64.6)

< 0.0001

 HPV mRNA pos /DNA neg = 8

 HPV mRNA neg/DNA pos = 49

 HPV mRNA neg/DNA neg = 104

II follow-up (Total Number n = 151)

 HPV mRNA pos/ DNA pos = 80

n = 58 (38.4%)

n = 93 (61.6%)

3.23 (1.4–7.2)

0.004

 HPV mRNA pos /DNA neg = 6

 HPV mRNA neg/DNA pos = 13

 HPV mRNA neg/DNA neg = 52

III follow-up (Total Number n = 90)

 HPV mRNA pos/ DNA pos = 46

n = 44 (48.4%)

N = 46 (51.2%)

10.3 (0.5–197.8)

0.12

 HPV mRNA neg/DNA neg = 44

  1. aIncluding HR-HPV mRNA and/or HPV DNA-negative patients
  2. b Including HR-HPV mRNA and/or HPV DNA-positive patients