Table 3 Univariable and multivariable Cox analysis of OS in skull base chordoma patients
Variables | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age (> 55 versus ≤55 years) | 1.852 | 1.072–3.198 | 0.027* | 1.791 | 1.023–3.135 | 0.042* |
Sex (female versus male) | 0.975 | 0.613–1.551 | 0.916 |  |  |  |
Tumour volume (> 20,000 versus ≤20000mm3) | 1.697 | 1.056–2.728 | 0.029* | NA | NA | 0.569 |
Texture (hard/moderate versus soft) | 1.612 | 0.935–2.780 | 0.086 |  |  |  |
Blood supply (poor/moderate versus rich) | 0.523 | 0.314–0.870 | 0.013* | NA | NA | 0.157 |
Pathology (chondroid versus classical) | 0.493 | 0.283–0.861 | 0.013* | NA | NA | 0.128 |
Brainstem involvement (yes versus no) | 1.013 | 0.630–1.629 | 0.956 |  |  |  |
Posterior cranial nerve involvement (yes versus no) | 1.287 | 0.802–2.064 | 0.295 |  |  |  |
Degree of resection (non-total versus total resection) | 3.390 | 1.552–7.405 | 0.002* | 2.585 | 1.172–5.704 | 0.019* |
Postoperative radiotherapy (yes versus no) | 0.794 | 0.479–1.317 | 0.371 |  |  |  |
Tumour recurrence (yes versus no) | 9.549 | 3.482–26.183 | < 0.001* | 7.460 | 2.701–20.599 | < 0.001* |
PLT (≥266 versus < 266) | 1.499 | 0.902–2.494 | 0.119 |  |  |  |
MPV (≥11.9 versus < 11.9) | 1.957 | 1.090–3.514 | 0.025* | NA | NA | 0.527 |
PDW (≥14.5 versus < 14.5) | 2.013 | 1.191–3.405 | 0.009* | 2.154 | 1.258–3.688 | 0.005* |