Mean platelet volume and platelet distribution width serve as prognostic biomarkers in skull base chordoma: a retrospective study

Table 1 Summary of 187 skull base chordoma patients

Variable	Number of patients
Age, years, mean ± SD	40.1 ± 15.3
Sex
Male	98
Female	89
Tumour volume, mm³, mean ± SD (range)	31,729.8 ± 33,238.5 (1740.4–258,024.6)
Most Common symptoms
Headache	88
Diplopia	68
Blurred vision	61
Vision field defect	43
Dizziness	30
Tumour texture
Soft	57
Hard/moderate	130
Tumour blood supply
Rich	109
Poor/moderate	78
Pathology type
Classical	126
Chondroid	61
Dedifferentiated	0
Brainstem involvement
No	69
Yes	118
Posterior cranial nerve involvement
No	118
Yes	69
Surgical approach
Endoscopic endonasal	73
Endoscopic transoral	6
Transcranial	108
Degree of resection
Total resection	41
Non-total resection	146
Postoperative radiotherapy
No	115
Yes	72
Gamma knife	42
Proton beam therapy	8
Carbon ion therapy	1
Cyberknife	1
Intensity modulated radiotherapy	4
Unknown	16
Median PLT, 10⁹/L (range)	234 (104–501)
Median MPV, fl (range)	10.2 (6.7–14.2)
Median PDW, % (range)	11.8 (7.8–26.2)
Death during follow up	72

SD standard deviation, PLT platelet count, MPV mean platelet volume, PDW platelet distribution width

ISSN: 1471-2407