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Fig. 3 | BMC Cancer

Fig. 3

From: The Axin2-snail axis promotes bone invasion by activating cancer-associated fibroblasts in oral squamous cell carcinoma

Fig. 3

Cytokines related to the Axin2-Snail axis exert strong influences on the biological behaviour of cancer-associated fibroblasts (CAFs) in vitro. a CAF identities were verified based on the expression of vimentin and α-SMA. b Proliferation was significantly increased after CCL5 or IL8 treatment in both CAF1 and CAF2 cells (i & ii). c Invasion ability and MMP-2 expression were significantly increased after IL8 treatment in both CAF1 (i-iii) and CAF2 (iv-vi) cells (original magnification, × 100; scale bar, 100 μm) (* p < 0.05)

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BMC Cancer

ISSN: 1471-2407

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