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Table 4 Univariate and multivariate analyses of DFS

From: The prognostic significance of inflammation-based scores in patients with ampullary carcinoma after pancreaticoduodenectomy

Characteristic Parameter Univariate analysis Multivariate analysis
HR(95% CI) P HR(95% CI) P
Gender Female / Male 1.042 (0.776–1.399) 0.706 NI
Age (years) <60/ ≥60 1.160 (0.866–1.555) 0.319 NI
NE(×109/L) <7/≥7 1.218 (0.864–1.717) 0.260 NI
LY(×109/L) <4/≥4 0.804 (0.330–1.955) 0.630 NI
HGB(g/L) <100/≥100 1.019 (0.765–1.358) 0.897 NI
PLT(×109/L) <300/≥300 1.017 (0.763–1.356) 0.907 NI
ALT(U/L) <40/≥40 1.395 (0.973–1.999) 0.070 NI
AST(U/L) <45/≥45 1.224 (0.875–1.712) 0.238 NI
ALP(U/L) <100/≥100 1.225 (0.798–1.881) 0.353 NI
GGT(U/L) <50/≥50 0.926 (0.598–1.433) 0.729 NI
ALB(g/L) <35/≥35 0.940 (0.665–1.330) 0.728 NI
TBIL (mmol/L) <20.5/≥20.5 1.118 (0.790–1.582) 0.529 NI
IBIL (mmol/L) <15/≥15 1.365 (1.024–1.821) 0.034 NI
CRP (mg/L) <8/≥8 1.291 (0.925–1.801) 0.133 NI
Tumor
differentiation
high/ moderate / poor 1.704 (1.296–2.240) <0.001 1.593 (1.185–2.141) 0.002
Tumor size (cm) <2/≥2 1.116 (0.914–1.363) 0.281 NI
Macrovascular Invision Absent/Present 2.216 (1.260–3.896) 0.006 1.758 (0.834–3.704) 0.138
Microvascular Invision Absent/Present 1.806 (0.897–1.245) 0.060 NI
LN metastasis Absent/Present 1.874 (1.404–2.500) <0.001 0.678 (0.363–1.266) 0.223
TNM Stage IA/IB/IIA/IIB/III 1.074 (1.181–1.467) <0.001 1.074 (0.848–1.361) 0.553
CEA (μg/L) <5/≥5 1.291 (1.179–2.172) 0.003 1.291 (0.935–1.782) 0.121
CA199(U/mL) <35/≥35 1.416 (1.351–2.848) <0.001 1.416 (0.959–2.093) 0.080
Chemotherapy Absent/Present 1.527 (1.145–2.036) 0.004 1.427 (1.056–1.928) 0.021
LNMS N0/N1/N2 1.639 (1.432–2.161) <0.001 1.639 (0.966–2.782) 0.067
PLNR ≤0.167/>0.167 1.178 (0.807–1.717) 0.396 NI
NLR ≤3.32 />3.32 1.406 (1.051–1.879) 0.022 1.450 (0.970–1.780) 0.078
dNLR ≤1.94/>1.94 1.207 (0.905–1.609) 0.200 NI
PLR ≤99.02/>99.02 2.432 (1.197–4.942) 0.014 2.040 (0.994–4.185) 0.052
PI 0 / 1 / 2 1.179 (0.941–1.479) 0.153 NI
PNI 0 / 1 1.021 (0.726–1.436) 0.906 NI
mGPS 0/1/2 1.077 (0.894–1.298) 0.436 NI
NLR-PI 1 / 2 / 3 1.304 (1.047–1.624) 0.018 1.285 (1.014–1.630) 0.038
  1. Abbreviations as in Table 3