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Table 4 Univariate and multivariate analyses of DFS

From: The prognostic significance of inflammation-based scores in patients with ampullary carcinoma after pancreaticoduodenectomy

Characteristic

Parameter

Univariate analysis

Multivariate analysis

HR(95% CI)

P

HR(95% CI)

P

Gender

Female / Male

1.042 (0.776–1.399)

0.706

–

NI

Age (years)

<60/ ≥60

1.160 (0.866–1.555)

0.319

–

NI

NE(×109/L)

<7/≥7

1.218 (0.864–1.717)

0.260

–

NI

LY(×109/L)

<4/≥4

0.804 (0.330–1.955)

0.630

–

NI

HGB(g/L)

<100/≥100

1.019 (0.765–1.358)

0.897

–

NI

PLT(×109/L)

<300/≥300

1.017 (0.763–1.356)

0.907

–

NI

ALT(U/L)

<40/≥40

1.395 (0.973–1.999)

0.070

–

NI

AST(U/L)

<45/≥45

1.224 (0.875–1.712)

0.238

–

NI

ALP(U/L)

<100/≥100

1.225 (0.798–1.881)

0.353

–

NI

GGT(U/L)

<50/≥50

0.926 (0.598–1.433)

0.729

–

NI

ALB(g/L)

<35/≥35

0.940 (0.665–1.330)

0.728

–

NI

TBIL (mmol/L)

<20.5/≥20.5

1.118 (0.790–1.582)

0.529

–

NI

IBIL (mmol/L)

<15/≥15

1.365 (1.024–1.821)

0.034

–

NI

CRP (mg/L)

<8/≥8

1.291 (0.925–1.801)

0.133

–

NI

Tumor

differentiation

high/ moderate / poor

1.704 (1.296–2.240)

<0.001

1.593 (1.185–2.141)

0.002

Tumor size (cm)

<2/≥2

1.116 (0.914–1.363)

0.281

–

NI

Macrovascular Invision

Absent/Present

2.216 (1.260–3.896)

0.006

1.758 (0.834–3.704)

0.138

Microvascular Invision

Absent/Present

1.806 (0.897–1.245)

0.060

–

NI

LN metastasis

Absent/Present

1.874 (1.404–2.500)

<0.001

0.678 (0.363–1.266)

0.223

TNM Stage

IA/IB/IIA/IIB/III

1.074 (1.181–1.467)

<0.001

1.074 (0.848–1.361)

0.553

CEA (μg/L)

<5/≥5

1.291 (1.179–2.172)

0.003

1.291 (0.935–1.782)

0.121

CA199(U/mL)

<35/≥35

1.416 (1.351–2.848)

<0.001

1.416 (0.959–2.093)

0.080

Chemotherapy

Absent/Present

1.527 (1.145–2.036)

0.004

1.427 (1.056–1.928)

0.021

LNMS

N0/N1/N2

1.639 (1.432–2.161)

<0.001

1.639 (0.966–2.782)

0.067

PLNR

≤0.167/>0.167

1.178 (0.807–1.717)

0.396

–

NI

NLR

≤3.32 />3.32

1.406 (1.051–1.879)

0.022

1.450 (0.970–1.780)

0.078

dNLR

≤1.94/>1.94

1.207 (0.905–1.609)

0.200

–

NI

PLR

≤99.02/>99.02

2.432 (1.197–4.942)

0.014

2.040 (0.994–4.185)

0.052

PI

0 / 1 / 2

1.179 (0.941–1.479)

0.153

–

NI

PNI

0 / 1

1.021 (0.726–1.436)

0.906

–

NI

mGPS

0/1/2

1.077 (0.894–1.298)

0.436

–

NI

NLR-PI

1 / 2 / 3

1.304 (1.047–1.624)

0.018

1.285 (1.014–1.630)

0.038

  1. Abbreviations as in Table 3