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Table 3 Univariate and multivariate analyses of OS

From: The prognostic significance of inflammation-based scores in patients with ampullary carcinoma after pancreaticoduodenectomy

Characteristic Parameter Univariate analysis Multivariate analysis
HR(95% CI) P HR(95% CI) P
Gender Female / Male 0.712 (0.492–1.032) 0.073 NI
Age (years) <60/ ≥60 1.570 (1.083–2.277) 0.017 1.492 (0.994–2.240) 0.054
NE(×109/L) <7/≥7 1.764 (1.171–2.657) 0.007 1.080 (0.620–1.883) 0.785
LY(×109/L) <4/≥4 0.788 (0.250–2.482) 0.684 NI
HGB(g/L) <100/≥100 0.869 (0.600–1.258) 0.458 NI
PLT(×109/L) <300/≥300 1.012 (0.699–1.466) 0.948 NI
ALT(U/L) <40/≥40 1.424 (0.894–2.270) 0.137 NI
AST(U/L) <45/≥45 1.279 (0.825–1.983) 0.272 NI
ALP(U/L) <100/≥100 1.171 (0.680–2.017) 0.568 NI
GGT(U/L) <50/≥50 0.953 (0.545–1.664) 0.867 NI
ALB(g/L) <35/≥35 0.976 (0.629–1.514) 0.914 NI
TBIL (mmol/L) <20.5/≥20.5 1.088 (0.701–1.688) 0.706 NI
IBIL (mmol/L) <15/≥15 1.493 (1.030–2.166) 0.035 1.345 (0.895–2.021) 0.154
CRP (mg/L) <8/≥8 1.189 (0.779–1.814) 0.422 NI
Tumor
differentiation
high/ moderate / poor 2.029 (1.421–2.895) <0.001 1.669 (1.126–2.476) 0.011
Tumor size (cm) <2/≥2 1.082 (0.837–1.397) 0.548 NI
Macrovascular Invision Absent/Present 1.998 (1.010–3.954) 0.047 1.521 (0.639–3.621) 0.344
Microvascular Invision Absent/Present 1.592 (1.080–2.347) 0.019 1.098 (0.708–1.703) 0.678
LN metastasis Absent/Present 1.545 (1.066–2.240) 0.022 0.640 (0.276–1.487) 0.299
TNM Stage IA/IB/IIA/IIB/III 1.208 (1.051–1.388) 0.008 1.035 (0.777–1.379) 0.814
CEA (μg/L) <5/≥5 1.356 (1.030–2.289) 0.035 1.172 (0.771–1.283) 0.457
CA199(U/mL) <35/≥35 2.075 (1.289–3.339) 0.003 1.250 (0.745–2.096) 0.398
Chemotherapy Absent/Present 0.816 (0.562–1.186) 0.286 NI
LNMS N0/N1/N2 1.574 (1.199–2.067) 0.001 1.786 (0.882–3.618) 0.107
PLNR ≤0.167/>0.167 1.367 (0.870–2.150) 0.176 NI
NLR ≤3.32/>3.32 1.599 (1.104–2.317) 0.013 0.820 (0.399–1.683) 0.588
dNLR ≤1.94/>1.94 1.451 (1.002–2.101) 0.049 0.894 (0.478–1.673) 0.726
PLR ≤99.02/>99.02 1.389 (0.676–2.853) 0.371 NI
PI 0 / 1 / 2 1.216 (0.906–1.633) 0.193 NI
PNI 0 / 1 1.063 (0.693–1.632) 0.778 NI
mGPS 0/1/2 0.996 (0.784–1.264) 0.971 NI
NLR-PI 1 / 2 / 3 1.570 (1.192–2.068) 0.001 1.684 (1.015–2.796) 0.044
  1. NE Neutrophilic granulocyte, LY Lymphocyte, GGT Glutamyltranspeptidase, ALP Alkaline phosphatase, LNMS Lymph node metastasis stage, PLNR Positive lymph node ratio. Other Abbreviations as in Table 1 and Table 2