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Table 4 Discriminatory performance of conventional scores and the nomogram for predicting grade B/C PHLF

From: Nomogram for prediction of the international study Group of Liver Surgery (ISGLS) grade B/C Posthepatectomy liver failure in HBV-related hepatocellular carcinoma patients: an external validation and prospective application study

 

Training Cohort

Internal validation Cohort

External validation Cohort

 

AUC

95% CI

P value

AUC

95% CI

P value

AUC

95% CI

P value

Child-Pugh

0.616

0.558–0.674

<0.001

0.608

0.502–0.715

0.043

0.541

0.467–0.615

0.267

MELD

0.647

0.597–0.697

<0.001

0.627

0.523–0.731

0.017

0.601

0.535–0.667

0.006

ALBI

0.689

0.635–0.743

<0.001

0.667

0.574–0.760

0.002

0.620

0.551–0.689

0.001

PALBI

0.634

0.580–0.687

<0.001

0.667

0.590–0.762

<0.001

0.668

0.603–0.732

<0.001

APRI

0.741

0.692–0.789

<0.001

0.734

0.640–0.827

<0.001

0.626

0.560–0.692

0.001

Nomogram

0.868

0.836–0.900

<0.001

0.867

0.809–0.925

<0.001

0.820

0.756–0.861

<0.001

  1. Abbreviations: MELD Model for end-stage liver disease, ALBI Albumin–bilirubin, PALBI Platelet-albumin-bilirubin, APRI Aspartate aminotransferase to platelet ratio index
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