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Table 4 Discriminatory performance of conventional scores and the nomogram for predicting grade B/C PHLF

From: Nomogram for prediction of the international study Group of Liver Surgery (ISGLS) grade B/C Posthepatectomy liver failure in HBV-related hepatocellular carcinoma patients: an external validation and prospective application study

  Training Cohort Internal validation Cohort External validation Cohort
  AUC 95% CI P value AUC 95% CI P value AUC 95% CI P value
Child-Pugh 0.616 0.558–0.674 <0.001 0.608 0.502–0.715 0.043 0.541 0.467–0.615 0.267
MELD 0.647 0.597–0.697 <0.001 0.627 0.523–0.731 0.017 0.601 0.535–0.667 0.006
ALBI 0.689 0.635–0.743 <0.001 0.667 0.574–0.760 0.002 0.620 0.551–0.689 0.001
PALBI 0.634 0.580–0.687 <0.001 0.667 0.590–0.762 <0.001 0.668 0.603–0.732 <0.001
APRI 0.741 0.692–0.789 <0.001 0.734 0.640–0.827 <0.001 0.626 0.560–0.692 0.001
Nomogram 0.868 0.836–0.900 <0.001 0.867 0.809–0.925 <0.001 0.820 0.756–0.861 <0.001
  1. Abbreviations: MELD Model for end-stage liver disease, ALBI Albumin–bilirubin, PALBI Platelet-albumin-bilirubin, APRI Aspartate aminotransferase to platelet ratio index