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Table 4 IC50 values of alvocidib in HL-60 cells

From: Venetoclax and alvocidib are both cytotoxic to acute myeloid leukemia cells resistant to cytarabine and clofarabine

Drug (nM)

IC 50 values in HL-60

Alvocidib âž” ara-C

989

Ara-C âž” Alvocidib

380

  1. Alvocidib ➔ ara-C; 50 nM alvocidib was added 24 h before ara-C,
  2. Ara-C ➔ Alvocidib; ara-C was added 24 h before 50 nM alvocidib
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BMC Cancer

ISSN: 1471-2407

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