Skip to main content

Table 4 IC50 values of alvocidib in HL-60 cells

From: Venetoclax and alvocidib are both cytotoxic to acute myeloid leukemia cells resistant to cytarabine and clofarabine

Drug (nM) IC 50 values in HL-60
Alvocidib ➔ ara-C 989
Ara-C ➔ Alvocidib 380
  1. Alvocidib ➔ ara-C; 50 nM alvocidib was added 24 h before ara-C,
  2. Ara-C ➔ Alvocidib; ara-C was added 24 h before 50 nM alvocidib