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Table 3 The growth inhibition effects of venetoclax and ara-C in MV4–11 cell line

From: Venetoclax and alvocidib are both cytotoxic to acute myeloid leukemia cells resistant to cytarabine and clofarabine

Drug (nM)

MV4–11

Venetoclax

692

Ara-C

3055

Venetoclax+ara-C

1012

  1. Cells were treated for 72 h with each agent at different concentrations,
  2. followed by the determination of IC50 using the XTT assay
  3. Venetoclax+ara-C; Cells were incubated for 72 h with 20 nM venetoclax
  4. CI was 0.42
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BMC Cancer

ISSN: 1471-2407

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