TY - JOUR AU - Nishi, Rie AU - Shigemi, Hiroko AU - Negoro, Eiju AU - Okura, Miyuki AU - Hosono, Naoko AU - Yamauchi, Takahiro PY - 2020 DA - 2020/10/12 TI - Venetoclax and alvocidib are both cytotoxic to acute myeloid leukemia cells resistant to cytarabine and clofarabine JO - BMC Cancer SP - 984 VL - 20 IS - 1 AB - Cytarabine (ara-C) is the major drug for the treatment of acute myeloid leukemia (AML), but cellular resistance to ara-C is a major obstacle to therapeutic success. The present study examined enhanced anti-apoptosis identified in 3 newly established nucleoside analogue-resistant leukemic cell line variants and approaches to overcoming this resistance. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-020-07469-x DO - 10.1186/s12885-020-07469-x ID - Nishi2020 ER -