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Table 2 Relationship between antibody expression and gene expression, gene mutation, gene amplification

From: Inducing multiple antibodies to treat squamous cell esophageal carcinoma

   

Elisa

TCGA

Gene Symbol

GenBank Accession number

Gene Description

Sensitivity (%)

Gene Expression

Mutation Frequency (%)

Gene Amplification (%)

p62

NM 003900

Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 KDa

5.9

normal < tumor

0

0

Annexin AII

NM 004039

Annexin A2

1.2

normal < tumor

0

0

c-myc

NM 002467

MYC Proto-Oncogene, BHLH Transcription Factor

2.4

normal < tumor

0

0

Cyclin B1

NM 031966

Cyclin B1

3.5

normal < tumor

0

0

LGALS1

NM 001540

Heat Shock Protein Family B (Small) Member 1

10.6

normal < tumor

0

0

HCA25a

AF 469043

Hepatocellulara carcinoma-associated antigens, HCA25a

9.4

N/A

N/A

N/A

HCC-22-5

NM 004683

Hepatocellulara carcinoma-associated antigens, HCC-22-5

8.2

N/A

N/A

N/A

HSP70

NM 004134

Heat Shock Protein Family A (Hsp70) Member 4

9.4

normal < tumor

0

0

KM-HN-1

NM 152775

Coiled-Coil Domain Containing 110

3.5

normal > tumor

1.85

0

Prx6

NM 004905

Peroxiredoxin 6

3.5

normal < tumor

0

0

Sui1

NM 005801

Eukaryotic Translation Initiation Factor 1

5.9

normal < tumor

0

0

VEGF

AF 486837

Vascular Endothelial Growth Factor A

0.0

normal < tumor

0

0

p90

AF 334474

Transferrin Receptor

5.9

normal < tumor

0

0

HSP40

NM 006145

DnaJ Heat Shock Protein Family (Hsp40) Member B1

8.2

normal < tumor

0.93

0

  1. Gene Expression: normal < tumor means that expression levels in tumor was signicicantly higher than the expression levels in normal tissue. Normal > tumor means that expression levels in tumor was signicicantly lower than the expression levels in normal tissue