Skip to main content

Table 4 Explorative analyses of factors associated with the acceptability of risk-based prevention

From: Dutch women’s intended participation in a risk-based breast cancer screening and prevention programme: a survey study identifying preferences, facilitators and barriers

Characteristic

Acceptability of risk-based prevention

Change diet

Increase exercise

Limit alcohol intake

Consider medication

Unadjusted

Multi-adjustedc

Unadjusted

Multi-adjustedc

Unadjusted

Multi-adjustedc

Unadjusted

Multi-adjustedc

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

Risk scenario

 Low

1.12 (0.76, 1.66)

1.10 (0.73, 1.68)

0.80 (0.52, 1.21)

0.76 (0.49, 1.18)

0.98 (0.64, 1.50)

1.08 (0.69, 1.68)

n/a

n/a

 Average

REF

REF

REF

REF

REF

REF

n/a

n/a

 Moderate

1.88 (1.27, 2.80)

1.95 (1.27, 2.98)

1.33 (0.88, 2.01)

1.30 (0.84, 2.00)

1.27 (0.84, 1.92)

1.32 (0.86, 2.04)

REF

REF

 High

1.72 (1.16, 2.56)

1.95 (1.28, 2.97)

1.28 (0.85, 1.93)

1.37 (0.89, 2.09)

1.77 (1.19, 2.65)

2.02 (1.33, 3.08)

1.44 (0.97, 2.13)

1.57 (1.03, 2.37)

Agef

0.98 (0.96, 1.00)

0.99 (0.96, 1.01)

0.98 (0.96, 1.00)

0.99 (0.96, 1.01)

1.01 (0.98, 1.03)

1.00 (0.98, 1.03)

0.98 (0.95, 1.01)

0.99d (0.96, 1.03)

Education

 Lower

REF

REF

REF

REF

REF

REF

REF

REF

 Higher secondary

1.21 (0.86, 1.72)

1.16 (0.79, 1.71)

1.86 (1.27, 2.73)

1.81 (1.20, 2.74)

1.41 (0.97, 2.06)

1.35 (0.90, 2.03)

1.33 (0.80, 2.19)

1.26 (0.73, 2.16)

 Higher vocational

0.97 (0.68, 1.38)

1.06 (0.71, 1.56)

1.93 (1.31, 2.85)

1.93 (1.27, 2.91)

2.03 (1.38, 2.97)

1.81 (1.21, 2.70)

1.38 (0.82, 2.32)

1.56 (0.89, 2.74)

BMIg

1.13 (1.09, 1.17)

1.12 (1.08, 1.17)

1.02 (0.99, 1.05)

1.02 (0.98, 1.05)

0.94 (0.91, 0.97)

0.95 (0.92, 0.98)

1.04 (1.00, 1.08)

1.03 (0.99, 1.08)

FDRb breast cancer

 No

REF

REF

REF

REF

REF

REF

REF

REF

 Yes

0.72 (0.51, 1.00)

0.63 (0.43, 0.93)

0.58 (0.40, 0.85)

0.55 (0.36, 0.84)

0.84 (0.59, 1.20)

0.90 (0.61, 1.33)

1.53 (0.94, 2.47)

1.31 (0.76, 2.25)

Benign breast disease

 No

REF

REF

REF

REF

REF

REF

REF

REF

 Yes

0.72 (0.53, 0.98)

0.88 (0.63, 1.23)

0.83 (0.60, 1.14)

0.86 (0.61, 1.22)

1.06 (0.77, 1.44)

0.99 (0.71, 1.38)

1.16 (0.74, 1.83)

1.26 (0.78, 2.04)

Co-morbidity

 0–1

REF

REF

REF

REF

REF

REF

REF

REF

  ≥ 2

1.13 (0.86, 1.49)

1.00 (0.73, 1.38)

1.14 (0.85, 1.53)

1.20 (0.87, 1.66)

0.79 (0.59, 1.05)

0.90 (0.65, 1.24)

1.23 (0.83, 1.82)

1.06 (0.69, 1.65)

General healthh

0.99 (0.98, 1.00)

0.99 (0.98, 1.01)

0.99 (0.98, 1.00)

0.99 (0.98, 1.00)

1.00 (0.99, 1.01)

1.00 (0.99, 1.01)

0.98 (0.97, 1.00)

0.99d (0.97, 1.01)

Life events

 0–1

REF

REF

REF

REF

REF

REF

REF

REF

  ≥ 2

1.15 (0.84, 1.56)

1.08 (0.78, 1.51)

1.01 (0.72, 1.40)

1.00 (0.70, 1.41)

0.92 (0.67, 1.26)

0.93 (0.66, 1.30)

1.06 (0.68, 1.66)

1.05 (0.65, 1.69)

Risk perception

 Below average

0.86 (0.65, 1.15)

0.92 (0.67, 1.26)

0.96 (0.71, 1.30)

0.97 (0.70, 1.34)

1.16 (0.86, 1.56)

1.04 (0.75, 1.43)

0.56 (0.37, 0.85)

0.65 (0.41, 1.01)

 Average

REF

REF

REF

REF

REF

REF

REF

REF

 Above average

1.96 (1.04, 3.68)

1.72 (0.85, 3.50)

1.23 (0.67, 2.27)

1.40 (0.71, 2.77)

1.04 (0.56, 1.90)

0.88 (0.45, 1.72)

1.21 (0.54, 2.69)

1.00 (0.41, 2.46)

Health anxietyi

1.05 (1.02, 1.09)

1.04 (1.00, 1.08)

1.03 (0.99, 1.06)

1.01 (0.97, 1.05)

1.02 (0.98, 1.06)

1.03 (0.99, 1.07)

1.04 (0.99, 1.09)

1.02 (0.96, 1.08)

Health locus of control

 No preference

REF

REF

REF

REF

REF

REF

REF

REF

 Internal

0.96 (0.60, 1.51)

0.94 (0.57, 1.55)

1.13 (0.70, 1.82)

1.05 (0.63, 1.75)

1.47 (0.91, 2.39)

1.50 (0.89, 2.53)

1.01 (0.50, 2.08)

0.98 (0.46, 2.09)

 Physician

2.25 (1.12, 4.50)

1.77 (0.82, 3.80)

2.23 (1.14, 4.36)

2.05 (0.99, 4.25)

1.24 (0.62, 2.46)

1.44 (0.68, 3.03)

1.23 (0.50, 3.04)

1.23 (0.46, 3.29)

 Chance

0.93 (0.60, 1.44)

1.01 (0.63, 1.64)

1.14 (0.72, 1.81)

1.19 (0.73, 1.95)

1.20 (0.75, 1.92)

1.27 (0.76, 2.10)

0.75 (0.38, 1.49)

0.66 (0.31, 1.38)

Current medication use

 No

      

REF

REF

 Yes

      

1.33 (0.89, 1.98)

1.00e (0.63, 1.59)

Beliefs about medicinesj

 Harm

      

0.87 (0.80, 0.94)

0.89d (0.82, 0.98)

 Overuse

      

0.86 (0.81, 0.92)

0.87d (0.81, 0.93)

  1. a Odds ratios in bold are significant with p < 0.05; bFDR = first degree relative; c Adjusted for age, education, BMI, FDR with breast cancer, benign breast disease, general health, risk perception, risk scenario, and health anxiety; d Additionally adjusted for current medication use; e Additionally adjusted for beliefs about medicines; f Age per 1 year increase; g BMI per one point increase; h General health per one point increase; I Health anxiety per one point increase; j Beliefs about medicines per one point increase