Skip to main content

Table 4 Explorative analyses of factors associated with the acceptability of risk-based prevention

From: Dutch women’s intended participation in a risk-based breast cancer screening and prevention programme: a survey study identifying preferences, facilitators and barriers

Characteristic Acceptability of risk-based prevention
Change diet Increase exercise Limit alcohol intake Consider medication
Unadjusted Multi-adjustedc Unadjusted Multi-adjustedc Unadjusted Multi-adjustedc Unadjusted Multi-adjustedc
OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Risk scenario
 Low 1.12 (0.76, 1.66) 1.10 (0.73, 1.68) 0.80 (0.52, 1.21) 0.76 (0.49, 1.18) 0.98 (0.64, 1.50) 1.08 (0.69, 1.68) n/a n/a
 Average REF REF REF REF REF REF n/a n/a
 Moderate 1.88 (1.27, 2.80) 1.95 (1.27, 2.98) 1.33 (0.88, 2.01) 1.30 (0.84, 2.00) 1.27 (0.84, 1.92) 1.32 (0.86, 2.04) REF REF
 High 1.72 (1.16, 2.56) 1.95 (1.28, 2.97) 1.28 (0.85, 1.93) 1.37 (0.89, 2.09) 1.77 (1.19, 2.65) 2.02 (1.33, 3.08) 1.44 (0.97, 2.13) 1.57 (1.03, 2.37)
Agef 0.98 (0.96, 1.00) 0.99 (0.96, 1.01) 0.98 (0.96, 1.00) 0.99 (0.96, 1.01) 1.01 (0.98, 1.03) 1.00 (0.98, 1.03) 0.98 (0.95, 1.01) 0.99d (0.96, 1.03)
Education
 Lower REF REF REF REF REF REF REF REF
 Higher secondary 1.21 (0.86, 1.72) 1.16 (0.79, 1.71) 1.86 (1.27, 2.73) 1.81 (1.20, 2.74) 1.41 (0.97, 2.06) 1.35 (0.90, 2.03) 1.33 (0.80, 2.19) 1.26 (0.73, 2.16)
 Higher vocational 0.97 (0.68, 1.38) 1.06 (0.71, 1.56) 1.93 (1.31, 2.85) 1.93 (1.27, 2.91) 2.03 (1.38, 2.97) 1.81 (1.21, 2.70) 1.38 (0.82, 2.32) 1.56 (0.89, 2.74)
BMIg 1.13 (1.09, 1.17) 1.12 (1.08, 1.17) 1.02 (0.99, 1.05) 1.02 (0.98, 1.05) 0.94 (0.91, 0.97) 0.95 (0.92, 0.98) 1.04 (1.00, 1.08) 1.03 (0.99, 1.08)
FDRb breast cancer
 No REF REF REF REF REF REF REF REF
 Yes 0.72 (0.51, 1.00) 0.63 (0.43, 0.93) 0.58 (0.40, 0.85) 0.55 (0.36, 0.84) 0.84 (0.59, 1.20) 0.90 (0.61, 1.33) 1.53 (0.94, 2.47) 1.31 (0.76, 2.25)
Benign breast disease
 No REF REF REF REF REF REF REF REF
 Yes 0.72 (0.53, 0.98) 0.88 (0.63, 1.23) 0.83 (0.60, 1.14) 0.86 (0.61, 1.22) 1.06 (0.77, 1.44) 0.99 (0.71, 1.38) 1.16 (0.74, 1.83) 1.26 (0.78, 2.04)
Co-morbidity
 0–1 REF REF REF REF REF REF REF REF
  ≥ 2 1.13 (0.86, 1.49) 1.00 (0.73, 1.38) 1.14 (0.85, 1.53) 1.20 (0.87, 1.66) 0.79 (0.59, 1.05) 0.90 (0.65, 1.24) 1.23 (0.83, 1.82) 1.06 (0.69, 1.65)
General healthh 0.99 (0.98, 1.00) 0.99 (0.98, 1.01) 0.99 (0.98, 1.00) 0.99 (0.98, 1.00) 1.00 (0.99, 1.01) 1.00 (0.99, 1.01) 0.98 (0.97, 1.00) 0.99d (0.97, 1.01)
Life events
 0–1 REF REF REF REF REF REF REF REF
  ≥ 2 1.15 (0.84, 1.56) 1.08 (0.78, 1.51) 1.01 (0.72, 1.40) 1.00 (0.70, 1.41) 0.92 (0.67, 1.26) 0.93 (0.66, 1.30) 1.06 (0.68, 1.66) 1.05 (0.65, 1.69)
Risk perception
 Below average 0.86 (0.65, 1.15) 0.92 (0.67, 1.26) 0.96 (0.71, 1.30) 0.97 (0.70, 1.34) 1.16 (0.86, 1.56) 1.04 (0.75, 1.43) 0.56 (0.37, 0.85) 0.65 (0.41, 1.01)
 Average REF REF REF REF REF REF REF REF
 Above average 1.96 (1.04, 3.68) 1.72 (0.85, 3.50) 1.23 (0.67, 2.27) 1.40 (0.71, 2.77) 1.04 (0.56, 1.90) 0.88 (0.45, 1.72) 1.21 (0.54, 2.69) 1.00 (0.41, 2.46)
Health anxietyi 1.05 (1.02, 1.09) 1.04 (1.00, 1.08) 1.03 (0.99, 1.06) 1.01 (0.97, 1.05) 1.02 (0.98, 1.06) 1.03 (0.99, 1.07) 1.04 (0.99, 1.09) 1.02 (0.96, 1.08)
Health locus of control
 No preference REF REF REF REF REF REF REF REF
 Internal 0.96 (0.60, 1.51) 0.94 (0.57, 1.55) 1.13 (0.70, 1.82) 1.05 (0.63, 1.75) 1.47 (0.91, 2.39) 1.50 (0.89, 2.53) 1.01 (0.50, 2.08) 0.98 (0.46, 2.09)
 Physician 2.25 (1.12, 4.50) 1.77 (0.82, 3.80) 2.23 (1.14, 4.36) 2.05 (0.99, 4.25) 1.24 (0.62, 2.46) 1.44 (0.68, 3.03) 1.23 (0.50, 3.04) 1.23 (0.46, 3.29)
 Chance 0.93 (0.60, 1.44) 1.01 (0.63, 1.64) 1.14 (0.72, 1.81) 1.19 (0.73, 1.95) 1.20 (0.75, 1.92) 1.27 (0.76, 2.10) 0.75 (0.38, 1.49) 0.66 (0.31, 1.38)
Current medication use
 No        REF REF
 Yes        1.33 (0.89, 1.98) 1.00e (0.63, 1.59)
Beliefs about medicinesj
 Harm        0.87 (0.80, 0.94) 0.89d (0.82, 0.98)
 Overuse        0.86 (0.81, 0.92) 0.87d (0.81, 0.93)
  1. a Odds ratios in bold are significant with p < 0.05; bFDR = first degree relative; c Adjusted for age, education, BMI, FDR with breast cancer, benign breast disease, general health, risk perception, risk scenario, and health anxiety; d Additionally adjusted for current medication use; e Additionally adjusted for beliefs about medicines; f Age per 1 year increase; g BMI per one point increase; h General health per one point increase; I Health anxiety per one point increase; j Beliefs about medicines per one point increase