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Table 3 Explorative analyses of factors associated with the acceptability of risk-based screening

From: Dutch women’s intended participation in a risk-based breast cancer screening and prevention programme: a survey study identifying preferences, facilitators and barriers

Characteristic Acceptability of risk-based breast cancer screening
Interest in risk Interest in supplemental screening Interest in breast self-examination
Unadjusted Multi-adjustedc Unadjusted Multi-adjustedc Unadjusted Multi-adjustedc
OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Risk scenario
 Low n/ad n/ad 0.58 (0.39, 0.86) 0.61 (0.41, 0.92) 0.28 (0.19, 0.41) 0.28 (0.19, 0.42)
 Average n/ad n/ad REF REF REF REF
 Moderate n/ad n/ad 1.53 (1.01, 2.21) 1.59 (1.09, 2.34) 4.79 (3.01, 7.64) 5.26 (3.25, 8.52)
 High n/ad n/ad 1.15 (0.79, 1.67) 1.23 (0.84, 1.81) 3.54 (2.29, 5.47) 4.32 (2.72, 6.86)
Agee 0.94 (0.91, 0.96) 0.94 (0.91, 0.97) 1.00 (0.97, 1.02) 0.99 (0.97, 1.02) 1.01 (0.99, 1.03) 1.00 (0.97, 1.03)
Education
 Lower REF REF REF REF REF REF
 Higher secondary 1.68 (1.11, 2.55) 1.21 (0.76, 1.90) 0.79 (0.57, 1.09) 0.72 (0.51, 1.03) 1.08 (0.77, 1.53) 1.00 (0.65, 1.53)
 Higher vocational 1.34 (0.89, 2.03) 1.04 (0.66, 1.61) 0.62 (0.44, 0.88) 0.58 (0.40, 0.84) 0.81 (0.57, 1.14) 0.66 (0.43, 1.01)
FDRb breast cancer
 No REF REF REF REF REF REF
 Yes 1.09 (0.72, 1.65) 0.97 (0.61, 1.53) 1.34 (0.98, 1.85) 1.28 (0.90, 1.81) 0.95 (0.69, 1.32) 1.00 (0.67, 1.52)
Benign breast disease
 No REF REF REF REF REF REF
 Yes 1.20 (0.82, 1.75) 1.25 (0.83, 1.88) 1.02 (0.77, 1.37) 0.98 (0.72, 1.34) 1.03 (0.77, 1.39) 1.24 (0.86, 1.78)
General healthf 0.99 (0.98, 1.00) 1.00 (0.98, 1.01) 1.00 (0.99, 1.01) 1.00 (0.99, 1.01) 1.01 (0.99, 1.01) 1.00 (0.99, 1.01)
Risk perception
 Below average n/ad n/ad 0.79 (0.60, 1.05) 0.90 (0.67, 1.22) 1.50 (1.12, 1.99) 1.83 (1.28, 2.60)
 Average n/ad n/ad REF REF REF REF
 Above average n/ad n/ad 1.75 (1.01, 3.02) 1.49 (0.82, 2.70) 1.23 (0.69, 2.17) 0.84 (0.42, 1.68)
Health anxietyg 1.05 (1.00, 1.09) 1.04 (0.99, 1.10) 1.03 (0.99, 1.06) 1.02 (0.99, 1.06) 1.01 (0.97, 1.04) 1.03 (0.98, 1.08)
Health locus of control
 No preference REF REF REF REF REF REF
 Internal 1.00 (0.55, 1.80) 0.85 (0.44, 1.64) 0.84 (0.54, 1.30) 0.98 (0.61, 1.56) 1.24 (0.79, 1.95) 1.17 (0.67, 2.03)
 Physician 0.56 (0.26, 1.18) 0.51 (0.22, 1.17) 0.74 (0.40, 1.37) 0.63 (0.32, 1.24) 2.86 (1.38, 5.94) 2.09 (0.87, 5.03)
 Chance 0.79 (0.45, 1.38) 0.74 (0.39, 1.39) 0.80 (0.52, 1.21) 0.87 (0.56, 1.37) 1.00 (0.65, 1.53) 0.82 (0.49, 1.39)
  1. a Odds ratios in bold are significant with p < 0.05; b FDR = first degree relative; c Adjusted for age, education, FDR with breast cancer, benign breast disease, general health, risk perception, risk scenario, and health anxiety; d analysis not available due to small subgroups (n < 10); e Age per 1 year increase; f General health per one point increase; g Health anxiety per one point increase