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Table 3 Explorative analyses of factors associated with the acceptability of risk-based screening

From: Dutch women’s intended participation in a risk-based breast cancer screening and prevention programme: a survey study identifying preferences, facilitators and barriers

Characteristic

Acceptability of risk-based breast cancer screening

Interest in risk

Interest in supplemental screening

Interest in breast self-examination

Unadjusted

Multi-adjustedc

Unadjusted

Multi-adjustedc

Unadjusted

Multi-adjustedc

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

Risk scenario

 Low

n/ad

n/ad

0.58 (0.39, 0.86)

0.61 (0.41, 0.92)

0.28 (0.19, 0.41)

0.28 (0.19, 0.42)

 Average

n/ad

n/ad

REF

REF

REF

REF

 Moderate

n/ad

n/ad

1.53 (1.01, 2.21)

1.59 (1.09, 2.34)

4.79 (3.01, 7.64)

5.26 (3.25, 8.52)

 High

n/ad

n/ad

1.15 (0.79, 1.67)

1.23 (0.84, 1.81)

3.54 (2.29, 5.47)

4.32 (2.72, 6.86)

Agee

0.94 (0.91, 0.96)

0.94 (0.91, 0.97)

1.00 (0.97, 1.02)

0.99 (0.97, 1.02)

1.01 (0.99, 1.03)

1.00 (0.97, 1.03)

Education

 Lower

REF

REF

REF

REF

REF

REF

 Higher secondary

1.68 (1.11, 2.55)

1.21 (0.76, 1.90)

0.79 (0.57, 1.09)

0.72 (0.51, 1.03)

1.08 (0.77, 1.53)

1.00 (0.65, 1.53)

 Higher vocational

1.34 (0.89, 2.03)

1.04 (0.66, 1.61)

0.62 (0.44, 0.88)

0.58 (0.40, 0.84)

0.81 (0.57, 1.14)

0.66 (0.43, 1.01)

FDRb breast cancer

 No

REF

REF

REF

REF

REF

REF

 Yes

1.09 (0.72, 1.65)

0.97 (0.61, 1.53)

1.34 (0.98, 1.85)

1.28 (0.90, 1.81)

0.95 (0.69, 1.32)

1.00 (0.67, 1.52)

Benign breast disease

 No

REF

REF

REF

REF

REF

REF

 Yes

1.20 (0.82, 1.75)

1.25 (0.83, 1.88)

1.02 (0.77, 1.37)

0.98 (0.72, 1.34)

1.03 (0.77, 1.39)

1.24 (0.86, 1.78)

General healthf

0.99 (0.98, 1.00)

1.00 (0.98, 1.01)

1.00 (0.99, 1.01)

1.00 (0.99, 1.01)

1.01 (0.99, 1.01)

1.00 (0.99, 1.01)

Risk perception

 Below average

n/ad

n/ad

0.79 (0.60, 1.05)

0.90 (0.67, 1.22)

1.50 (1.12, 1.99)

1.83 (1.28, 2.60)

 Average

n/ad

n/ad

REF

REF

REF

REF

 Above average

n/ad

n/ad

1.75 (1.01, 3.02)

1.49 (0.82, 2.70)

1.23 (0.69, 2.17)

0.84 (0.42, 1.68)

Health anxietyg

1.05 (1.00, 1.09)

1.04 (0.99, 1.10)

1.03 (0.99, 1.06)

1.02 (0.99, 1.06)

1.01 (0.97, 1.04)

1.03 (0.98, 1.08)

Health locus of control

 No preference

REF

REF

REF

REF

REF

REF

 Internal

1.00 (0.55, 1.80)

0.85 (0.44, 1.64)

0.84 (0.54, 1.30)

0.98 (0.61, 1.56)

1.24 (0.79, 1.95)

1.17 (0.67, 2.03)

 Physician

0.56 (0.26, 1.18)

0.51 (0.22, 1.17)

0.74 (0.40, 1.37)

0.63 (0.32, 1.24)

2.86 (1.38, 5.94)

2.09 (0.87, 5.03)

 Chance

0.79 (0.45, 1.38)

0.74 (0.39, 1.39)

0.80 (0.52, 1.21)

0.87 (0.56, 1.37)

1.00 (0.65, 1.53)

0.82 (0.49, 1.39)

  1. a Odds ratios in bold are significant with p < 0.05; b FDR = first degree relative; c Adjusted for age, education, FDR with breast cancer, benign breast disease, general health, risk perception, risk scenario, and health anxiety; d analysis not available due to small subgroups (n < 10); e Age per 1 year increase; f General health per one point increase; g Health anxiety per one point increase