TY - JOUR AU - Siegel, R. L. AU - Miller, K. D. AU - Jemal, A. PY - 2019 DA - 2019// TI - Cancer statistics, 2019 JO - CA Cancer J Clin VL - 69 ID - Siegel2019 ER - TY - JOUR AU - Bray, F. AU - Ferlay, J. AU - Soerjomataram, I. AU - Siegel, R. L. AU - Torre, L. A. AU - Jemal, A. PY - 2018 DA - 2018// TI - Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries JO - CA Cancer J Clin VL - 68 UR - https://doi.org/10.3322/caac.21492 DO - 10.3322/caac.21492 ID - Bray2018 ER - TY - STD TI - Ben-David U, AA-Ohoo A. Context is everything: aneuploidy in cancer. Nat Rev Genet. 2019;21(1):44–62. ID - ref3 ER - TY - JOUR AU - Rieder, C. L. AU - Khodjakov, A. PY - 1997 DA - 1997// TI - Mitosis and checkpoints that control progression through mitosis in vertebrate somatic cells JO - Prog Cell Cycle Res VL - 3 UR - https://doi.org/10.1007/978-1-4615-5371-7_24 DO - 10.1007/978-1-4615-5371-7_24 ID - Rieder1997 ER - TY - JOUR AU - Rudner, A. D. AU - Murray, A. W. PY - 1996 DA - 1996// TI - The spindle assembly checkpoint JO - Curr Opin Cell Biol VL - 8 UR - https://doi.org/10.1016/S0955-0674(96)80077-9 DO - 10.1016/S0955-0674(96)80077-9 ID - Rudner1996 ER - TY - JOUR AU - Silva, P. AU - Barbosa, J. AU - Nascimento, A. V. AU - Faria, J. AU - Reis, R. AU - Bousbaa, H. PY - 2011 DA - 2011// TI - Monitoring the fidelity of mitotic chromosome segregation by the spindle assembly checkpoint JO - Cell Prolif VL - 44 UR - https://doi.org/10.1111/j.1365-2184.2011.00767.x DO - 10.1111/j.1365-2184.2011.00767.x ID - Silva2011 ER - TY - STD TI - Henriques AC, Ribeiro D, Pedrosa J, Sarmento B, Silva PMA, Bousbaa H. Mitosis inhibitors in anticancer therapy: when blocking the exit becomes a solution. Cancer Lett. 2019;440-441:64-81. ID - ref7 ER - TY - JOUR AU - Weaver, B. A. AU - Cleveland, D. W. PY - 2006 DA - 2006// TI - Does aneuploidy cause cancer? JO - Curr Opin Cell Biol VL - 18 UR - https://doi.org/10.1016/j.ceb.2006.10.002 DO - 10.1016/j.ceb.2006.10.002 ID - Weaver2006 ER - TY - JOUR AU - Okamoto, Y. AU - Ozaki, T. AU - Miyazaki, K. AU - Aoyama, M. AU - Miyazaki, M. AU - Nakagawara, A. PY - 2003 DA - 2003// TI - UbcH10 is the cancer-related E2 ubiquitin-conjugating enzyme JO - Cancer Res VL - 63 ID - Okamoto2003 ER - TY - JOUR AU - Wagner, K. W. AU - Sapinoso, L. M. AU - El-Rifai, W. PY - 2004 DA - 2004// TI - Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin JO - Oncogene VL - 23 UR - https://doi.org/10.1038/sj.onc.1207861 DO - 10.1038/sj.onc.1207861 ID - Wagner2004 ER - TY - JOUR AU - Pallante, P. AU - Berlingieri, M. T. AU - Troncone, G. PY - 2005 DA - 2005// TI - UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas JO - Br J Cancer VL - 93 UR - https://doi.org/10.1038/sj.bjc.6602721 DO - 10.1038/sj.bjc.6602721 ID - Pallante2005 ER - TY - JOUR AU - Zhao, L. AU - Jiang, L. AU - Wang, L. PY - 2012 DA - 2012// TI - UbcH10 expression provides a useful tool for the prognosis and treatment of non-small cell lung cancer JO - J Cancer Res Clin Oncol VL - 138 UR - https://doi.org/10.1007/s00432-012-1275-2 DO - 10.1007/s00432-012-1275-2 ID - Zhao2012 ER - TY - JOUR AU - Ree, J. H. AU - Jeganathan, K. B. AU - Malureanu, L. AU - Deursen, J. M. PY - 2010 DA - 2010// TI - Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation JO - J Cell Biol VL - 188 UR - https://doi.org/10.1083/jcb.200906147 DO - 10.1083/jcb.200906147 ID - Ree2010 ER - TY - JOUR AU - Alfieri, C. AU - Chang, L. AU - Zhang, Z. PY - 2016 DA - 2016// TI - Molecular basis of APC/C regulation by the spindle assembly checkpoint JO - Nature VL - 536 UR - https://doi.org/10.1038/nature19083 DO - 10.1038/nature19083 ID - Alfieri2016 ER - TY - JOUR AU - Liu, L. AU - Chen, X. AU - Xie, S. AU - Zhang, C. AU - Qiu, Z. AU - Zhu, F. PY - 2012 DA - 2012// TI - Variant 1 of KIAA0101, overexpressed in hepatocellular carcinoma, prevents doxorubicin-induced apoptosis by inhibiting p53 activation JO - Hepatology (Baltimore, Md) VL - 56 UR - https://doi.org/10.1002/hep.25834 DO - 10.1002/hep.25834 ID - Liu2012 ER - TY - JOUR AU - Kato, T. AU - Daigo, Y. AU - Aragaki, M. AU - Ishikawa, K. AU - Sato, M. AU - Kaji, M. PY - 2012 DA - 2012// TI - Overexpression of KIAA0101 predicts poor prognosis in primary lung cancer patients JO - Lung Cancer (Amsterdam, Netherlands) VL - 75 UR - https://doi.org/10.1016/j.lungcan.2011.05.024 DO - 10.1016/j.lungcan.2011.05.024 ID - Kato2012 ER - TY - JOUR AU - Emanuele, M. J. AU - Ciccia, A. AU - Elia, A. E. AU - Elledge, S. J. PY - 2011 DA - 2011// TI - Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate JO - Proc Natl Acad Sci U S A VL - 108 UR - https://doi.org/10.1073/pnas.1106136108 DO - 10.1073/pnas.1106136108 ID - Emanuele2011 ER - TY - JOUR AU - Marques, S. AU - Fonseca, J. AU - Silva, P. M. AU - Bousbaa, H. PY - 2015 DA - 2015// TI - Targeting the spindle assembly checkpoint for breast cancer treatment JO - Curr Cancer Drug Targets VL - 15 UR - https://doi.org/10.2174/1568009615666150302130010 DO - 10.2174/1568009615666150302130010 ID - Marques2015 ER - TY - JOUR AU - Colombo, R. AU - Caldarelli, M. AU - Mennecozzi, M. PY - 2010 DA - 2010// TI - Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase JO - Cancer Res VL - 70 UR - https://doi.org/10.1158/0008-5472.CAN-10-2101 DO - 10.1158/0008-5472.CAN-10-2101 ID - Colombo2010 ER - TY - STD TI - Zheng L, Chen Z, Kawakami M, et al. Threonine tyrosine kinase inhibition eliminates lung cancers by augmenting apoptosis and polyploidy. Mol Cancer Ther. 2019;18(10):1775-86. ID - ref20 ER - TY - JOUR AU - Reddy, S. K. AU - Rape, M. AU - Margansky, W. A. AU - Kirschner, M. W. PY - 2007 DA - 2007// TI - Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation JO - Nature VL - 446 UR - https://doi.org/10.1038/nature05734 DO - 10.1038/nature05734 ID - Reddy2007 ER - TY - JOUR AU - King, E. M. AU - Sar, S. J. AU - Hardwick, K. G. PY - 2007 DA - 2007// TI - Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint JO - PLoS One VL - 2 UR - https://doi.org/10.1371/journal.pone.0000342 DO - 10.1371/journal.pone.0000342 ID - King2007 ER - TY - JOUR AU - Diaz-Martinez, L. A. AU - Yu, H. PY - 2007 DA - 2007// TI - Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint JO - Cell Div VL - 2 UR - https://doi.org/10.1186/1747-1028-2-23 DO - 10.1186/1747-1028-2-23 ID - Diaz-Martinez2007 ER -