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Table 4 Head and neck SPCs in CIN 2–3 LLETZ treated women. A comparison between literature and our study data

From: Risk of HPV-related extra-cervical cancers in women treated for cervical intraepithelial neoplasia

Author

Year

First lesion

Value

Head and Neck

Evans [26]

2003

CIN 3

SIR

1.2

Kalliala [6]

2005

CIN 1–3

SIR

1.7

Gaudet [10]

2014

CIN 2

SIR

0.47

  

CIN 3

SIR

0.67

Ebisch [8]

2017

CIN 3

IRR

5.51

Suk [23]

2018

SCC

SIR

1.4

Wang [16]

2020

SCC

SIR

2.29

Our study

 

CIN 2–3

SIR

8.5

  1. Legenda:
  2. CIN Cervical Intraepithelial Neoplasia
  3. IRR Incidence Rate Ratio
  4. LLETZ Large Loop Excision of the Transformation Zone
  5. SCC Invasive Squamous Cell Carcinoma
  6. SIR Standardized Incidence Ratio