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Table 2 HPV-related cancers in CIN 2–3 LLETZ treated patients. Standardized Incidence Rates according to Haenszel’s formula

From: Risk of HPV-related extra-cervical cancers in women treated for cervical intraepithelial neoplasia

Cancer Site

ICDO-3 codes

Observed SPCs

Expected SPCs

SIR

95% CI

Oropharynx

C01-C10

5

0.59

8.5

2.76–19.8

Anus

C21

1

0.55

1.8

0.04–10.0

Vulva

C51

1

0.58

1.7

0.04–9.59

Vagina

C52

3

0.24

12.4

2.56–36.3

Total

 

10

1.96

5.1

2.44–9.38

  1. Legenda:
  2. ICDO-3 International Classification of Diseases for Oncology 3rd Edition
  3. LLETZ Large Loop Excision of the Transformation Zone
  4. SPCs Second Primary Cancers
  5. SIR Standardized Incidence Ratio
  6. CI Confidence Interval