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Table 2 HPV-related cancers in CIN 2–3 LLETZ treated patients. Standardized Incidence Rates according to Haenszel’s formula

From: Risk of HPV-related extra-cervical cancers in women treated for cervical intraepithelial neoplasia

Cancer Site ICDO-3 codes Observed SPCs Expected SPCs SIR 95% CI
Oropharynx C01-C10 5 0.59 8.5 2.76–19.8
Anus C21 1 0.55 1.8 0.04–10.0
Vulva C51 1 0.58 1.7 0.04–9.59
Vagina C52 3 0.24 12.4 2.56–36.3
Total   10 1.96 5.1 2.44–9.38
  1. Legenda:
  2. ICDO-3 International Classification of Diseases for Oncology 3rd Edition
  3. LLETZ Large Loop Excision of the Transformation Zone
  4. SPCs Second Primary Cancers
  5. SIR Standardized Incidence Ratio
  6. CI Confidence Interval