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Table 1 Observed subsequent cancers in a cohort of patients treated with LLETZ for CIN2–3 [excluding non-melanoma skin cancers]

From: Risk of HPV-related extra-cervical cancers in women treated for cervical intraepithelial neoplasia

Cancer Site ICDO-3 codes Observed SPCs
Oropharynx C01-C10 5
Oesophagus C15 1
Colon-rectum C18–20 20
Anus C21 1
Liver C22 1
Gallbladder C24 2
Pancreas C25 1
Lung C33-C34 15
Melanoma C44 11
Soft Tissues C49 1
Breast C50 62
Vulva C51 1
Vagina C52 3
Corpus Uteri C54 9
Ovary C56 7
Kidney C64 2
Bladder C67 3
SNC C71 1
Thyroid C73 6
Parathyroid C75 1
Myeloma C42 5
Lymphomas C77 9
Leukaemias C42 2
Others   4
Total   173
  1. Legenda:
  2. ICDO-3 International Classification of Diseases for Oncology 3rd Edition
  3. LLETZ Large Loop Excision of the Transformation Zone
  4. SPCs Second Primary Cancers