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Fig. 6 | BMC Cancer

Fig. 6

From: Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer

Fig. 6

Proposed model of anti-tumor immunity induced by NF-κB activation in tumor-associated macrophages. Activation of NF-κB signaling in tumor-associated macrophages induces polarization of macrophages away from the M2 and towards the anti-tumor M1 phenotype, and also leads to recruitment of cytotoxic T cells, mediated at least in part through increased levels of CXCL9. Figure 6 was created by the authors with BioRender.com

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BMC Cancer

ISSN: 1471-2407

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