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Fig. 5 | BMC Cancer

Fig. 5

From: HOXD-AS1 facilitates cell migration and invasion as an oncogenic lncRNA by competitively binding to miR-877-3p and upregulating FGF2 in human cervical cancer

Fig. 5

MiR-877-3p/FGF2 reversed the effects of HOXD-AS1 on CC cell migration and invasion. a miR-877-3p and HOXD-AS1 expressions were examined using qRT-PCR after rescuing the expression of miR-877-3p. b Cell migration and invasion abilities were reduced after rescuing the expression of miR-877-3p in HOXD-AS1-overexpression group by wound healing and transwell assays. c FGF2 protein expression was examined using western bolt analysis after rescuing the expression of miR-877-3p. (D) FGF2 and HOXD-AS1 expressions were examined using qRT-PCR after knocking down the expression of FGF2. (E) Cell migration and invasion abilities were reduced after knocking down the expression of FGF2 in HOXD-AS1-overexpression group by wound healing and transwell assays. **: P < 0.01, ***: P < 0.001, ##: P < 0.01 vs 3.1-HOXD-AS1 group, ###: P < 0.001 vs 3.1-HOXD-AS1 group, NS: not significant

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