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Fig. 3 | BMC Cancer

Fig. 3

From: HOXD-AS1 facilitates cell migration and invasion as an oncogenic lncRNA by competitively binding to miR-877-3p and upregulating FGF2 in human cervical cancer

Fig. 3

HOXD-AS1 directly interacted with miR-877-3p in CC cells. a The wild type (in green) and mutant type (in red) binding sites between HOXD-AS1 and miR-877-3p were obtained from the bioinformatics software LncBase v.2. b qRT-PCR was performed to measure the effect of miR-877-3p on HOXD-AS1 expression in Hela cells transfected with miR-877-3p mimics (miR-877-3p-M) and miR-877-3p inhibitor (miR-877-3p-M-I). c Dual luciferase reporter activity was detected after co-transfection with miR-877-3p and wild type HOXD-AS1 (HOXD-AS1-wt) or mutant type HOXD-AS1 (HOXD-AS1-mt). **: P < 0.01, ***: P < 0.001

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