Fig. 1

Heavy tobacco exposure decreases overall and disease free survival for patients with HPV + OPC. Kaplan-Meier curves of overall survival ‘OS’ (a) and disease-free survival ‘DFS’ (b) for the entire cohort stratified by human papillomavirus (HPV) status; and OS (c) and DFS (d) for the entire cohort stratified by HPV status and tobacco exposure. Kaplan-Meier survival curves confidence intervals are represented by shades of the corresponding group color