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Table 3 Rebiopsy outcomes

From: Genetic diagnostic features after failure of initial treatment with epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors among non-small-cell lung cancer patients harboring EGFR mutations

Variable

T790M mutation

 

Positive patients (n = 29)

Negative patients (n = 17)

Total patients (n = 46)

Tissue biopsy (included cytology) count

31

12

43

T790M positive count

24 (77.4)

24 (55.8)

  With Original mutation

22

22

  Without Original mutation

2

2

T790M negative count

7 (22.6)

12

19 (44.2)

  With Original mutation

5

10

15

  Without Original mutation

2

2

4

Liquid biopsy count

58

40

98

T790M positive count

11 (19.0)

11 (11.2)

  With Original mutation

10

10

  Without Original mutation

1

1

T790M negative count

47 (81.0)

40

87 (88.8)

  With Original mutation

9

11

20

  Without Original mutation

38

29

67

Total rebiopsy count

89

52

141

  1. Data are number of patients (%) unless specified otherwise