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Table 3 Rebiopsy outcomes

From: Genetic diagnostic features after failure of initial treatment with epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors among non-small-cell lung cancer patients harboring EGFR mutations

Variable T790M mutation  
Positive patients (n = 29) Negative patients (n = 17) Total patients (n = 46)
Tissue biopsy (included cytology) count 31 12 43
T790M positive count 24 (77.4) 24 (55.8)
  With Original mutation 22 22
  Without Original mutation 2 2
T790M negative count 7 (22.6) 12 19 (44.2)
  With Original mutation 5 10 15
  Without Original mutation 2 2 4
Liquid biopsy count 58 40 98
T790M positive count 11 (19.0) 11 (11.2)
  With Original mutation 10 10
  Without Original mutation 1 1
T790M negative count 47 (81.0) 40 87 (88.8)
  With Original mutation 9 11 20
  Without Original mutation 38 29 67
Total rebiopsy count 89 52 141
  1. Data are number of patients (%) unless specified otherwise