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Table 6 Prognostic factors for event-free survival of 89 MS-LCH patients who received systemic chemotherapy through univariate and multivariate cox regression *Only factors with a P value < 0.1 in univariate analysis were listed

From: Clinical presentation and prognostic analysis of adult patients with Langerhans cell histiocytosis with pulmonary involvement

 

Univariate Cox

Multivariate Cox

 

HR (95% CI)

P value

HR (95% CI)

P value

Smoking status

0.517 (0.257–1.042)

0.065

0.553 (0.269–1.141)

0.109

More than 3 organs involved

1.818 (0.920–3592)

0.080

1.647 (0.718–3.777)

0.239

Pneumothorax

1.989 (1.012–3.910)

0.046

3.203 (1.454–7.053)

0.004

Spleen

2.159 (0.884–5.276)

0.091

1.630 (0.605–4.394)

0.334

Cytarabine based therapy

0.525 (0.262–1.053)

0.065

0.325 (0.141–0.749)

0.008

  1. MS Multisystem disease