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Table 6 Prognostic factors for event-free survival of 89 MS-LCH patients who received systemic chemotherapy through univariate and multivariate cox regression *Only factors with a P value < 0.1 in univariate analysis were listed

From: Clinical presentation and prognostic analysis of adult patients with Langerhans cell histiocytosis with pulmonary involvement

  Univariate Cox Multivariate Cox
  HR (95% CI) P value HR (95% CI) P value
Smoking status 0.517 (0.257–1.042) 0.065 0.553 (0.269–1.141) 0.109
More than 3 organs involved 1.818 (0.920–3592) 0.080 1.647 (0.718–3.777) 0.239
Pneumothorax 1.989 (1.012–3.910) 0.046 3.203 (1.454–7.053) 0.004
Spleen 2.159 (0.884–5.276) 0.091 1.630 (0.605–4.394) 0.334
Cytarabine based therapy 0.525 (0.262–1.053) 0.065 0.325 (0.141–0.749) 0.008
  1. MS Multisystem disease