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Table 5 Prognostic factors for overall survival of 89 MS-LCH patients who received systemic chemotherapy through univariate and multivariate cox regression *Only factors with a P value < 0.1 in univariate analysis were listed

From: Clinical presentation and prognostic analysis of adult patients with Langerhans cell histiocytosis with pulmonary involvement

  Univariate Cox Multivariate Cox
  HR (95% CI) P value HR (95% CI) P value
Age at diagnosis 1.080 (1.010–1.155) 0.024 1.051 (0.923–1.197) 0.453
FEV1 ≤ 55% 14.882 (1.339–164.037) 0.028 12.487 (1.131–137.822) 0.039
TLC 0.907 (0.832–0.988) 0.025 0.864 (0.703–1.061) 0.162
Cytarabine based therapy 0.127 (0.024–0.662) 0.014 0.151 (0.009–2.456) 0.184
  1. MS Multisystem disease