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Table 3 Pulmonary function parameters of LCH patients with pulmonary involvement at diagnosis

From: Clinical presentation and prognostic analysis of adult patients with Langerhans cell histiocytosis with pulmonary involvement

Pulmonary function test N = 74
Normal, n (%) 12 (16.2)
Restrictive disorders, n (%) 19 (25.7)
Obstructive disorders, n (%) 12 (16.2)
Defective diffusing capacity, n (%) 60 (81.1)
Isolated diffusing capacity defect, n (%) 33 (44.6)
Restrictive and diffusing capacity defect, n (%) 16 (21.6)
Obstructive and diffusing capacity defect, n (%) 9 (12.2)
Mixed ventilation and diffusing capacity defect, n(%) 2 (2.7)
DLCO, % of predicted (median, range) 65.1 (27.6–119.0)
FEV1, % of predicted (median, range) 82.7 (26–109.8)
FEV1/FVC, % (median, range) 79.90 (50.75–106.0)
TLC, % of predicted (median, range) 87.4 (51.9–188.1)