Table 3 Pulmonary function parameters of LCH patients with pulmonary involvement at diagnosis
Pulmonary function test | N = 74 |
|---|---|
Normal, n (%) | 12 (16.2) |
Restrictive disorders, n (%) | 19 (25.7) |
Obstructive disorders, n (%) | 12 (16.2) |
Defective diffusing capacity, n (%) | 60 (81.1) |
Isolated diffusing capacity defect, n (%) | 33 (44.6) |
Restrictive and diffusing capacity defect, n (%) | 16 (21.6) |
Obstructive and diffusing capacity defect, n (%) | 9 (12.2) |
Mixed ventilation and diffusing capacity defect, n(%) | 2 (2.7) |
DLCO, % of predicted (median, range) | 65.1 (27.6–119.0) |
FEV1, % of predicted (median, range) | 82.7 (26–109.8) |
FEV1/FVC, % (median, range) | 79.90 (50.75–106.0) |
TLC, % of predicted (median, range) | 87.4 (51.9–188.1) |