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Fig. 6 | BMC Cancer

Fig. 6

From: Metabolic characterization of aggressive breast cancer cells exhibiting invasive phenotype: impact of non-cytotoxic doses of 2-DG on diminishing invasiveness

Fig. 6

Low dose of glycolysis inhibitor, 2-DG, diminished BC invasion Cells were treated with 0.3 or 1 mM 2-DG for 16 h, and surviving fraction, and invasiveness were determined. Ratio of surviving vs. control (no 2-DG treatment), and percent of invaded cells with representative image were shown for SUM149 (a), MDA-MB-231 (b), and HCC1937 (c), respectively. Data are presented as mean ± SDs of triplicate samples. *p < 0.05, **p < 0.01, ***p < 0.001. Scale bar: 200 μm

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