Fig. 5

Inhibitor for TCA cycle and ETC had no significant effects on BC invasiveness Cells were treated with 0.25, 0.75, or 1.5 mM 3-NA for 16 h, and surviving fraction, and invasiveness were studied. Ratio of surviving vs. control (no 3-NA treatment), and percent of invaded cells with representative image of invaded cells reached underneath of the transwell membrane were shown for SUM149 (a), MDA-MB-231 (b), and HCC1937 (c), respectively. Data are presented as mean ± SDs of triplicate samples. Scale bar: 200 μm