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Fig. 2 | BMC Cancer

Fig. 2

From: Metabolic characterization of aggressive breast cancer cells exhibiting invasive phenotype: impact of non-cytotoxic doses of 2-DG on diminishing invasiveness

Fig. 2

SUM149 INV cells showed hyper-glycolytic phenotype compared to WCC. a Principal component analysis of metabolites detected in WCC versus INV was performed and is shown in the graph (n = 3). b Metabolomics profile of WCC and INV were analyzed by CE-TOFMS. The concentrations of glycolytic intermediates measured in WCC or INV are shown in graph. Y axis represents the metabolite concentration in pmol / 10^6 cells. Data are presented as mean ± SD of samples (n = 3). ***p < 0.001 vs. WCC., N.D.: Not detected

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