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Table 3 Comparisons of IL-10, IL-12, and IFN-γ levels in tumor tissues among groups and at different time points (pg/mL, mean ± S)

From: Relationship between the invasion of lymphocytes and cytokines in the tumor microenvironment and the interval after single brachytherapy hypofractionated radiotherapy and conventional fractionation radiotherapy in non-small cell lung Cancer

Groups

n

IL-10 levels

IL-12 levels

IFN-γ levels

Day 7 (ratio,%)

Day 14 (ratio,%)

Day 7 (ratio,%)

Day 14 (ratio,%)

Day 7 (ratio,%)

Day 14 (ratio,%)

Control

6

190.9 ± 53.0

257.4 ± 65.4

18.1 ± 4.3

17.4 ± 2.0

201.9 ± 39.7

184.9 ± 31.6

CFRT*

6

155.3 ± 48.8 (−18.6)

219.9 ± 54.1 (− 14.6)

21.7 ± 2.5# (+19.9)

19.1 ± 1.9 (+ 9.8)

222.2 ± 38.8 (+ 10.1)

210.8 ± 36.1 (+ 14.0)

SBHFRTҰ

6

91.6 ± 31.5#※ (− 52.0 /− 41.0)

135.8 ± 47.6#※ (− 47.2 /− 38.2)

26.8 ± 2.8#※ (+ 48.1 /+ 23.5)

22.5 ± 2.5#※ (+ 29.3 /+ 17.8)

348.4 ± 53.9#※ (+ 72.6 /+ 56.8)

270.7 ± 44.6#※ (+ 46.4 /+ 28.4)

F

 

7.38

7.38

19.68

8.70

18.94

8.11

P

 

0.01

0.01

0.00

0.00

0.00

0.00

  1. *Conventional fractionation radiotherapy
  2. ҰSingle brachytherapy hypofractionated radiotherapy
  3. #Compared with the control group, p < 0.05
  4. Compared with theCFRT group, p < 0.05
  5. Ratiocompared with the control group
  6. Ratiocompared with the CFRT group
  7. Increasing
  8. Decreasing