| Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|
P | HR | 95.0% CI | P | ||
Age | |||||
  < 65 | Reference | Reference |  |  |  |
 65–76 | 0.416 | 1.25 | 0.83–1.88 | 0.277 | |
  > 76 | < 0.001 | 3.26 | 2.19–4.85 | < 0.001 | |
Tumor size | |||||
  < 7.4 | Reference | Reference |  |  |  |
 7.4–12.4 | 0.036 | 2.42 | 1.43–4.10 | 0.001 | |
  > 12.4 | < 0.001 | 3.73 | 2.32–6.01 | < 0.001 | |
Race | |||||
 Black | Reference |  |  |  |  |
 Other | 0.609 |  |  |  |  |
 White | 0.668 |  |  |  |  |
Sex | |||||
 Female | Reference | Reference |  |  | |
 Male | 0.001 | 1.42 | 1.01–2.00 | 0.047 | |
Histological type | |||||
 Liposarcoma, NOS | Reference |  |  |  |  |
 Liposarcoma, well differentiated | < 0.001 |  |  |  |  |
 Myxoid liposarcoma | 0.668 |  |  |  |  |
 Round cell liposarcoma | < 0.001 |  |  |  |  |
 Pleomorphic liposarcoma | < 0.001 |  |  |  |  |
 Mixed liposarcoma | 0.024 |  |  |  |  |
 Fibroblastic liposarcoma | 0.966 |  |  |  |  |
 Dedifferentiated liposarcoma | 0.002 |  |  |  |  |
AJCC | |||||
 I/II | Reference |  |  |  |  |
 III/IV | < 0.001 |  |  |  |  |
T | |||||
 T1 | Reference |  |  |  |  |
 T2 | 0.007 |  |  |  |  |
N | |||||
 N0 | Reference |  |  |  |  |
 N1 | 0.088 |  |  |  |  |
M | |||||
 M0 | Reference | Reference |  |  | |
 M1 | < 0.001 | 5.83 | 3.37–10.09 | < 0.001 | |
Surgery | |||||
 No | Reference | Reference |  |  | |
 Yes | < 0.001 | 0.43 | 0.21–0.85 | 0.015 | |
Radiotherapy | |||||
 No | Reference |  |  |  |  |
 Yes | < 0.001 |  |  |  |  |
Chemotherapy | |||||
 No | Reference |  |  |  |  |
 Yes | < 0.001 |  |  |  |  |
Primary site | |||||
 Lower extremity | Reference |  |  |  |  |
 Upper extremity | 0.768 |  |  |  |  |
Grade | |||||
 I | Reference | Reference |  |  |  |
 II | < 0.001 | 3.95 | 2.13–7.33 | < 0.001 | |
 III | < 0.001 | 14.10 | 8.34–23.85 | < 0.001 | |
 IV | < 0.001 | 19.02 | 11.41–31.71 | < 0.001 |