| Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|
P | HR | 95.0% CI | P | ||
Age | |||||
  < 65 | Reference | Reference |  |  |  |
 65–76 | < 0.001 | 1.91 | 1.41–2.58 | < 0.001 | |
  > 76 | < 0.001 | 5.64 | 4.23–7.53 | < 0.001 | |
Tumor size | |||||
  < 11.1 | Reference | Reference |  |  |  |
 11.1–23.5 | 0.022 | 1.69 | 1.29–2.22 | < 0.001 | |
  > 23.5 | < 0.001 | 2.52 | 1.77–3.57 | < 0.001 | |
Race | |||||
 Black | Reference |  |  |  |  |
 Other | 0.426 |  |  |  |  |
 White | 0.668 |  |  |  |  |
Sex | |||||
 Female | Reference | Reference |  |  | |
 Male | 0.002 | 1.43 | 1.11–1.84 | 0.006 | |
Histological type | |||||
 Liposarcoma, NOS | Reference |  |  |  |  |
 Liposarcoma, well differentiated | 0.001 |  |  |  |  |
 Myxoid liposarcoma | 0.327 |  |  |  |  |
 Round cell liposarcoma | 0.005 |  |  |  |  |
 Pleomorphic liposarcoma | < 0.001 |  |  |  |  |
 Mixed liposarcoma | 0.256 |  |  |  |  |
 Fibroblastic liposarcoma | 0.951 |  |  |  |  |
 Dedifferentiated liposarcoma | < 0.001 |  |  |  |  |
AJCC | |||||
 I/II | Reference |  |  |  |  |
 III/IV | < 0.001 |  |  |  |  |
T | |||||
 T1 | Reference |  |  |  |  |
 T2 | 0.273 |  |  |  |  |
N | |||||
 N0 | Reference |  |  |  | |
 N1 | 0.063 |  |  |  | |
M | |||||
 M0 | Reference | Reference |  |  | |
 M1 | < 0.001 | 4.97 | 2.92–8.46 | < 0.001 | |
Surgery | |||||
 No | Reference | Reference |  |  | |
 Yes | < 0.001 | 0.33 | 0.20–0.55 | < 0.001 | |
Radiotherapy | |||||
 No | Reference |  |  |  |  |
 Yes | < 0.001 |  |  |  |  |
Chemotherapy | |||||
 No | Reference |  |  |  |  |
 Yes | < 0.001 |  |  |  |  |
Primary site | |||||
 Lower extremity | Reference |  |  |  |  |
 Upper extremity | 0.730 |  |  |  |  |
Grade | |||||
 I | Reference | Reference |  |  |  |
 II | 0.312 | 1.83 | 1.22–2.74 | 0.004 | |
 III | < 0.001 | 4.90 | 3.53–6.80 | < 0.001 | |
 IV | < 0.001 | 5.85 | 4.27–8.02 | < 0.001 |