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Fig. 3 | BMC Cancer

Fig. 3

From: USP6NL mediated by LINC00689/miR-142-3p promotes the development of triple-negative breast cancer

Fig. 3

MiR-142-3p plays a tumor repressive part in TNBC. a. Colony formation assay was performed to assess the impact of miR-142-3p upregulation on cell proliferation. b-d. Under the context of miR-142-3p elevation, cell apoptosis was tested via flow cytometry analysis, JC-1 assay and TUNEL assay. The X axis of the FACS dot plots in Fig. 3b meant cells labelled with FITC and the Y axis indicated cells dyed by PI. e-f. The effect of enhanced miR-142-3p on cell migration and invasion was tested via transwell assays. g. IF assay analyzed the expression of two EMT-related proteins (E-cadherin and N-cadherin) in TNBC cells with or without miR-142-3p up-regulation. **P < 0.01

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