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Table 4 GO functional and KEGG pathway enrichment analysis of pseudogenes-related protein-coding genes

From: Development and validation of a novel pseudogene pair-based prognostic signature for prediction of overall survival in patients with hepatocellular carcinoma

ID

Description

P value

P adjust

GO:0004896

cytokine receptor activity

1.64E-11

6.31E-09

GO:0001637

G protein-coupled chemoattractant receptor activity

4.05E-08

3.23E-06

GO:0004950

chemokine receptor activity

4.05E-08

3.23E-06

GO:0019955

cytokine binding

4.21E-08

3.23E-06

GO:0016493

C-C chemokine receptor activity

1.65E-07

9.05E-06

GO:0019957

C-C chemokine binding

2.54E-07

1.30E-05

GO:0019956

chemokine binding

3.92E-07

1.88E-05

GO:0023023

MHC protein complex binding

6.72E-07

3.04E-05

GO:0042287

MHC protein binding

1.33E-06

5.67E-05

GO:0032395

MHC class II receptor activity

2.54E-05

0.001027582

GO:0030246

carbohydrate binding

0.000143695

0.004598232

GO:0001608

G protein-coupled nucleotide receptor activity

0.000175825

0.005193614

GO:0045028

G protein-coupled purinergic nucleotide receptor activity

0.000175825

0.005193614

GO:0030695

GTPase regulator activity

0.000508907

0.012607749

KEGG:hsa04662

B cell receptor signaling pathway

4.67E-12

1.85E-10

KEGG:hsa04062

Chemokine signaling pathway

2.79E-09

4.07E-08

KEGG:hsa04660

T cell receptor signaling pathway

1.36E-07

1.45E-06

KEGG:hsa04650

Natural killer cell mediated cytotoxicity

3.92E-07

4.02E-06

KEGG:hsa04060

Cytokine-cytokine receptor interaction

1.07E-06

1.03E-05

KEGG:hsa04064

NF-kappa B signaling pathway

0.000577911

0.00390442

KEGG:hsa05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

0.001387015

0.008934958

KEGG:hsa05231

Choline metabolism in cancer

0.008939182

0.047618336