Table 3 Univariate and multivariate analyses identified independent prognostic factors for overall survival of HCC in the TCGA and the ICGC cohorts

1.01

0.996–1.025

0.174

1.01

0.996–1.024

0.168

0.776

0.531–1.132

0.188

0.912

0.614–1.353

0.646

1.133

0.881–1.456

0.33

0.927

0.706–1.219

0.588

1.68

1.369–2.062

< 0.0001

1.33

1.070–1.654

0.01

3.583

2.726–4.709

< 0.0001

3.416

2.551–4.576

< 0.0001

0.515

0.270–0.982

0.044

0.42

0.215–0.819

0.011

0.998

0.966–1.032

0.917

0.989

0.955–1.025

0.558

2.238

1.532–3.269

< 0.0001

2.16

1.459–3.198

0.0001

1.658

0.692–3.975

0.257

2.287

0.912–5.734

0.078

0.794

0.404–1.563

0.505

0.706

0.351–1.421

0.329

2.337

1.490–3.664

0.0002

1.902

1.201–3.014

0.006