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Table 2 Clinical characteristics of patients according to PLR

From: High platelet-to-lymphocyte ratio is associated with poor prognosis in patients with unresectable intrahepatic cholangiocarcinoma receiving gemcitabine plus cisplatin

Variable

PLR ≤148 (N = 74)

PLR > 148 (N = 63)

P value

Age, yr

64 (58, 73)

64 (54, 69)

0.247

Sex

  

1.000

 Male

45 (60.8%)

38 (60.3%)

 

 Female

29 (39.2%)

25 (39.7%)

 

BMI

23.7 (22.2, 25.7)

23.0 (22.0, 24.5)

0.119

ECOG Performance status

  

1.000

 0

35 (47.3%)

29 (46.0%)

 

  ≥ 1

39 (52.7%)

34 (54.0%)

 

Liver cirrhosis

10 (13.5%)

5 (7.9%)

0.443

Diabetes mellitus

15 (20.3%)

10 (15.9%)

0.658

Charlson Commorbidity Index

  

0.595

 0

45 (60.8%)

42 (66.7%)

 

  ≥ 1

29 (39.2%)

21 (33.3%)

 

Biliary drainage

6 (8.1%)

9 (14.3%)

0.379

Tumor size, cm

7.2 (5.4, 10.0)

7.0 (4.5, 9.6)

0.246

Major vascular invasion

53 (71.6%)

36 (57.1%)

0.112

Hilar invasion

9 (12.2%)

7 (11.1%)

1.000

Liver metastasis

27 (36.5%)

28 (44.4%)

0.440

Extrahepatic organ metastasis

38 (51.4%)

37 (58.7%)

0.489

Distant lymph node metastasis

47 (63.5%)

43 (68.3%)

0.688

Number of metastatic sites

  

0.090

 0

10 (13.5%)

2 (3.2%)

 

 1

27 (36.5%)

23 (36.5%)

 

  ≥ 2

37 (50.0%)

38 (60.3%)

 

Baseline laboratory findings

 Neutrophil count, cells/μL

5288 (3768, 6403)

5792 (4663, 7231)

0.063

 Lymphocyte count, cells/μL

1935 (1547, 2271)

1377 (1119, 1623)

< 0.001

 Monocyte count, cells/μL

637 (509, 808)

629 (506, 756)

0.837

 Platelet count, 103 cells/μL

199 (163, 255)

261 (224, 303)

< 0.001

 Total bilirubin, mg/dL

0.7 (0.6, 0.9)

0.7 (0.5, 0.9)

0.979

 ALP, IU/L

129 (93, 225)

164 (115, 259)

0.074

 Albumin, g/dL

4.0 (3.7, 4.2)

3.8 (3.5, 4.1)

0.030

 CA 19–9, U/mL

652.5 (44.6, 4830.0)

183.4 (16.1, 2955.0)

0.211

  1. Abbreviations: PLR Platelet-to-lymphocyte ratio; BMI Body mass index; ECOG Eastern Cooperative Oncology Group; ALP Alkaline phosphatase; CA 19–9 Carbohydrate antigen 19–9
  2. Data are presented as no. (%) or median (interquartile range)